65903-66-4 Usage
General Description
1,2-Pyrrolidinedicarboxylic acid, 1-(phenylmethyl) 2-[2-(trimethylsilyl)ethyl] ester, (S)- is a chemical compound used in pharmaceutical research and drug development. It is an ester derivative of pyrrolidine and is commonly used as a chiral building block in the synthesis of various pharmaceuticals. The compound is known for its role as an intermediate in the synthesis of enantiomerically pure compounds and is used in the manufacturing of drugs with potential therapeutic applications. It is also used in the production of chiral auxiliaries and catalysts, making it an important compound in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 65903-66-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,9,0 and 3 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 65903-66:
(7*6)+(6*5)+(5*9)+(4*0)+(3*3)+(2*6)+(1*6)=144
144 % 10 = 4
So 65903-66-4 is a valid CAS Registry Number.
65903-66-4Relevant academic research and scientific papers
Application of substituted 2-(trimethylsilyl)ethyl esters to suppress diketopiperazine formation
Borsuk, Katarzyna,Van Delft, Floris L.,Eggen, Ivo F.,Ten Kortenaar, Paul B. W.,Petersen, Annet,Rutjes, Floris P.J.T.
, p. 3585 - 3588 (2007/10/03)
The use of differently substituted 2-(trimethylsilyl)ethyl esters for C-terminal protection in peptide synthesis has been investigated. While the use of the unsubstituted 2-(trimethylsilyl)ethyl ester resulted in a substantial amount of diketopiperazine a
