65906-75-4

Usage

InChI:InChI=1/C11H17FN2O5/c1-3-5-6-19-8-11(12,9(16)18-4-2)7(15)13-10(17)14-8/h8H,3-6H2,1-2H3,(H2,13,14,15,17)

Upstream product

• 65905-97-7 5-ethoxycarbonyl-5-fluoro-6-hydroxy-5,6-dihydrouracil 
• 71-36-3 butan-1-ol 
• 38026-46-9 ethyl 4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxilate 
• 65905-97-7 (4S,5R)-5-Fluoro-4-hydroxy-2,6-dioxo-hexahydro-pyrimidine-5-carboxylic acid ethyl ester 
• 70759-40-9 (+/-)-t-6-acetoxy-r-5-ethoxycarbonyl-5-fluoro-5,6-dihydrouracil 
• 28485-17-8 5-carbethoxyuracil 
• 70759-40-9 ethyl 6-acetoxy-5-fluoro-1,2,3,4,5,6-hexahydro-2,4-dioxopyrimidine-5-carboxylate 

Downstream Products

• 51-21-8 5-fluorouracil 

Relevant academic research and scientific papers

Uracil derivatives and production thereof

New derivatives of the formula: STR1 (wherein X is O or NH; R1 is --OH which may optionally be etherified or esterified, etherified mercapto or --NH2 which may optionally be substituted; R2 and R3, respectively, mean H, lower alkyl or STR2 and Y is an esterified or amidated carboxyl group, or CN). These derivatives are produced, by fluorination of corresponding 1,2,3,4-tetrahydro-2,4-dioxopyrimidine compounds and can be converted into 5-fluorouracil derivatives under hydrolytic conditions. The new derivatives are able to prolong the lives of animals having carcinomas or have antiviral activity.