65948-16-5Relevant academic research and scientific papers
Helical, twisting power of new chiral dopants having a trifluoromethyl group at the chiral center for nematic liquid crystals
Aoki, Yoshio,Matsushima, Kentarou,Taroura, Tetsu,Hirose, Takuji,Nohira, Hiroyuki
, p. 189 - 193 (2003)
New chiral dopants for nematic liquid crystals were synthesized using optically active 4,4,4-trifluoro-3-phenylbutanaic acid. The magnitude of helical twisting power (HTP) was largely influenced by the linkage between the asymmetric frame and the core moiety. The chiral dopant, 4,4,4-trifluoro-1-(4-hexyloxy-phenyl)-3-phenyl-1-butanone showed extremely large HTP value (21.0 μm-1).
Ruthenium-catalyzed one-pot tandem isomerization-transfer hydrogenation reactions of γ-trifluoromethylated allylic alcohols and β-trifluoromethylated enones
Bizet, Vincent,Pannecoucke, Xavier,Renaud, Jean-Luc,Cahard, Dominique
supporting information, p. 1394 - 1402 (2013/07/19)
The ruthenium-2-propanol combination was found to transform γ-trifluoromethylated allylic alcohols and β-trifluoromethylated enones into the corresponding saturated alcohols in excellent yields via a one-pot tandem process involving isomerization and transfer hydrogenation(s). High stereospecificity was demonstrated and evidence for two mechanistic pathways is provided. The method was applied to a rapid synthesis of trifluoromethylated citronellol. Copyright
