659745-75-2Relevant academic research and scientific papers
Design, synthesis and activity of novel derivatives of Oxybutynin and Tolterodine
Kaur, Kirandeep,Aeron, Shelly,Bruhaspathy, Miriyala,Shetty, Shankar J.,Gupta, Suman,Hegde, Laxminarayan H.,Silamkoti, Arun D. V.,Mehta, Anita,Chugh, Anita,Gupta, Jang B.,Sarma,Kumar, Naresh
, p. 2093 - 2096 (2005)
Novel derivatives of Tolterodine (1) and Oxybutynin (2) have been designed using conformationally restricted azabicyclics as replacement for open-chain amines. The synthesis and structure-activity relationships are presented.
3,6-DISUBSTITUTED AZABICYCLO [3.1.0] HEXANE DERIVATIVES USEFUL AS MUSCARINIC RECEPTOR ANTAGONIST
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Page/Page column 13, (2008/06/13)
This invention generally relates to the derivatives of 3,6 disubstituted azabicyclo[3.1.0] hexanes. The compounds of this invention are muscarinic receptor antagonists which are useful, inter-alia, for the treatment of various diseases of the respiratory,
