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2',3'-dideoxycytidine 5'-triphosphate, also known as ddCTP, is a nucleoside analog that functions by inhibiting the activity of DNA polymerase, thereby terminating DNA chain elongation. This unique property makes it a valuable asset in molecular biology research and a potential candidate for antiviral therapeutics.

66004-77-1

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66004-77-1 Usage

Uses

Used in Molecular Biology Research:
2',3'-dideoxycytidine 5'-triphosphate is used as a sequencing tool for DNA sequencing and PCR applications. Its inability to form a phosphodiester bond with the incoming nucleotide due to the lack of a 3' hydroxyl group results in the termination of DNA synthesis, which is crucial for determining the sequence of DNA strands.
Used in Antiviral Therapeutics:
2',3'-dideoxycytidine 5'-triphosphate is used as a potential antiviral agent, particularly against retroviruses such as HIV. When incorporated into viral DNA, it inhibits the replication process, showcasing its potential in the development of antiviral treatments.

Check Digit Verification of cas no

The CAS Registry Mumber 66004-77-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,0,0 and 4 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 66004-77:
(7*6)+(6*6)+(5*0)+(4*0)+(3*4)+(2*7)+(1*7)=111
111 % 10 = 1
So 66004-77-1 is a valid CAS Registry Number.
InChI:InChI=1/C9H16N3O12P3/c10-7-3-4-12(9(13)11-7)8-2-1-6(22-8)5-21-26(17,18)24-27(19,20)23-25(14,15)16/h3-4,6,8H,1-2,5H2,(H,17,18)(H,19,20)(H2,10,11,13)(H2,14,15,16)/t6-,8+/m0/s1

66004-77-1 Well-known Company Product Price

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  • Sigma-Aldrich

  • (02241)  2′,3′-Dideoxycytidine5′-triphosphatesodiumsaltsolution  for MALDI MS, ≥98.0% (HPLC)

  • 66004-77-1

  • 02241-1UMO-F

  • 4,376.97CNY

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66004-77-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name Triphosphoric acid, mono[[(2S,5R)-5-(4-amino-2-oxo-1(2H)-pyrimidi nyl)tetrahydro-2-furanyl]methyl] ester

1.2 Other means of identification

Product number -
Other names 5-I-ddU

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:66004-77-1 SDS

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