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N,N'-DI-SEC-BUTYLCARBODIIMIDE, also known as DSCD, is a white crystalline solid with a molecular formula C12H23N3 and a molecular weight of 209.33 g/mol. It is a powerful and versatile reagent for amide bond formation in organic synthesis, particularly in the synthesis of peptides, pharmaceuticals, and other bioactive compounds. DSCD functions by activating carboxylic acids to form highly reactive acylating agents for coupling with amines, resulting in the formation of stable amide bonds. Known for its high efficiency and low racemization in peptide coupling reactions, DSCD is a valuable tool in organic chemistry research and peptide synthesis.

66006-67-5

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66006-67-5 Usage

Uses

Used in Organic Synthesis:
N,N'-DI-SEC-BUTYLCARBODIIMIDE is used as a peptide coupling reagent for the formation of stable amide bonds in the synthesis of peptides, pharmaceuticals, and other bioactive compounds. It activates carboxylic acids to form highly reactive acylating agents, which couple with amines to create the desired amide bonds.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, N,N'-DI-SEC-BUTYLCARBODIIMIDE is used as a key reagent in the synthesis of various drugs and bioactive compounds. Its high efficiency and low racemization properties make it an essential tool for the development of new pharmaceuticals and the improvement of existing ones.
Used in Peptide Synthesis:
N,N'-DI-SEC-BUTYLCARBODIIMIDE is used as a coupling agent in peptide synthesis, facilitating the formation of amide bonds between amino acids. Its ability to activate carboxylic acids and couple with amines makes it a preferred choice for the synthesis of peptides with high purity and yield.
Used in Bioactive Compounds Synthesis:
In the synthesis of bioactive compounds, N,N'-DI-SEC-BUTYLCARBODIIMIDE is used as a reagent for the formation of amide bonds, which are crucial for the biological activity of many compounds. Its versatility and efficiency in activating carboxylic acids and coupling with amines make it an indispensable tool in the development of new bioactive compounds with potential therapeutic applications.

Check Digit Verification of cas no

The CAS Registry Mumber 66006-67-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,0,0 and 6 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 66006-67:
(7*6)+(6*6)+(5*0)+(4*0)+(3*6)+(2*6)+(1*7)=115
115 % 10 = 5
So 66006-67-5 is a valid CAS Registry Number.
InChI:InChI=1/C9H18N2/c1-5-8(3)10-7-11-9(4)6-2/h8-9H,5-6H2,1-4H3

66006-67-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name N,N'-di(butan-2-yl)methanediimine

1.2 Other means of identification

Product number -
Other names di-sec-butyl-carbodiimide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:66006-67-5 SDS

66006-67-5Downstream Products

66006-67-5Relevant academic research and scientific papers

Methods of dissolving blood clots and the like with streptokinase chemically bonded to a carbohydrate matrix

-

, (2008/06/13)

One part by weight of streptokinase is chemically bonded to one to five hundred parts by weight of a carbohydrate, to form a material which has improved stability compared with free streptokinase.

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