66016-70-4

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Basic information

Product Name: (-)-BICUCULLINE METHBROMIDE
Synonyms: (-)-BICUCULLINE METHBROMIDE;[r-(r*,s*)]-5-(6,8-dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl)-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquindinium bromide;1(s),9(r)-(-)-bicuculline methobromide;(5S)-5-[(6R)-6,8-Dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl]-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquinolinium bromide (1:1);1(S),9(R)-(-)-Bicuculline methbromide
CAS NO:66016-70-4
Molecular Formula: C21H20NO6.Br
Molecular Weight: 462.294
EINECS: N/A
Product Categories: N/A
Mol File: 66016-70-4.mol
Article Data: 0

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: white/solid
Density: N/A
Refractive Index: N/A
Storage Temp.: 2-8°C
Solubility: aqueous base: unstable
CAS DataBase Reference: (-)-BICUCULLINE METHBROMIDE(CAS DataBase Reference)
NIST Chemistry Reference: (-)-BICUCULLINE METHBROMIDE(66016-70-4)
EPA Substance Registry System: (-)-BICUCULLINE METHBROMIDE(66016-70-4)

Safety Data

Hazard Codes: T+,N
Statements: 24-28-50
Safety Statements: 24/25-61-45-36/37-28
RIDADR: UN 1544 6.1/PG 2
WGK Germany: 3
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 66016-70-4(Hazardous Substances Data)

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Cas No: 66016-70-4
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Zhuozhou Wenxi import and Export Co., Ltd
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1(S),9(R)-(-)-BICUCULLINE METHBROMIDE
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BOC Sciences
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(-)-BICUCULLINE METHBROMIDECAS
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Hangzhou Fandachem Co.,Ltd
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(-)-BICUCULLINE METHBROMIDE
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ZHEJIANG JIUZHOU CHEM CO.,LTD
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66016-70-4 Usage

Uses

1(S),9(R)-(-)-Bicuculline methbromide has been used:as a γ-aminobutyric acid (GABAA) receptor A antagonist: in cortical neuron culturein artificial cerebrospinal fluid (ACSF) formature dentate granule neuronsin hypothalamic explant cultures

Biochem/physiol Actions

1(S),9(R)-(?)-Bicuculline methbromide is a GABAA receptor antagonist, which blocks Ca2+-activated potassium (SK) channels. It is the water-soluble derivative of (+)-bicuculline.

Check Digit Verification of cas no

The CAS Registry Mumber 66016-70-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,0,1 and 6 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 66016-70:
(7*6)+(6*6)+(5*0)+(4*1)+(3*6)+(2*7)+(1*0)=114
114 % 10 = 4
So 66016-70-4 is a valid CAS Registry Number.

InChI:InChI=1/C21H20NO6.BrH/c1-22(2)6-5-11-7-15-16(26-9-25-15)8-13(11)18(22)19-12-3-4-14-20(27-10-24-14)17(12)21(23)28-19;/h3-4,7-8,18-19H,5-6,9-10H2,1-2H3;1H/q+1;/p-1

66016-70-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name	(6R)-6-[(5S)-6,6-dimethyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl]-6H-furo[3,4-g][1,3]benzodioxol-8-one,bromide

1.2 Other means of identification

Product number	-
Other names	(-)-Bicuculline methbromide,1(S),9(R)

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:66016-70-4 SDS

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