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Benzenemethanol, 2-fluoro-6-hydroxy-, also known as 2-fluoro-6-hydroxybenzenemethanol or 6-hydroxy-2-fluorobenzyl alcohol, is an organic compound with the chemical formula C7H7FO2. It features a benzene ring with a hydroxyl group at the 6-position, a fluorine atom at the 2-position, and a hydroxymethyl group attached to the benzene ring. Benzenemethanol, 2-fluoro-6-hydroxy- is a valuable intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other specialty chemicals due to its unique combination of functional groups. It is typically synthesized through various chemical reactions, such as nucleophilic substitution or electrophilic aromatic substitution, and can be used in the preparation of more complex molecules with potential applications in various industries.

660390-77-2

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660390-77-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 660390-77-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,6,0,3,9 and 0 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 660390-77:
(8*6)+(7*6)+(6*0)+(5*3)+(4*9)+(3*0)+(2*7)+(1*7)=162
162 % 10 = 2
So 660390-77-2 is a valid CAS Registry Number.

660390-77-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-fluorosalicyl alcohol

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:660390-77-2 SDS

660390-77-2Downstream Products

660390-77-2Relevant academic research and scientific papers

Efficient and selective reduction protocols of the 2,2-dimethyl-1,3- benzodioxan-4-one functional group to readily provide both substituted salicylaldehydes and 2-hydroxybenzyl alcohols

Bajwa, Naval,Jennings, Michael P.

, p. 3646 - 3649 (2007/10/03)

Two complementary procedures have been developed that selectively allow for the synthesis of either substituted salicylaldehydes or the corresponding 2-hydroxylbenzyl alcohols upon treatment of the 2,2-dimethyl-1,3-benzodioxan-4- one functional group with DIBAL-H or LAH, respectively.

3,5-Di-(tert-Butyl)-6-fluoro-cycloSal-d4TMP - A Pronucleotide with a Considerably Improved Masking Group

Ducho, Christian,Wendicke, Silke,Goerbig, Ulf,Balzarini, Jan,Meier, Chris

, p. 4786 - 4791 (2007/10/03)

A new, considerably improved cycloSal masking group has been developed. This new group combines four desirable properties and has been attached to the anti-HIV drug 2′,3′-dideoxy-2′,3′-didehydrothymidine (d4T, 1) to give 3,5-(di-tert-butyl)-6-fluoro-cycloSal-d4TMP (2i). This phosphate triester has a reasonable chemical half-life, highly selectively released d4TMP, has poor - if any - inhibitory effect on butyrylcholinesterase (BChE), and achieved the TK-bypass. ( Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003).

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