660441-76-9

Upstream product

• 674803-04-4 2-N-(4-methylsulfonylbenzoyl)-amide-5-chloro-4'-methylsulfonylbenzophenone 

Downstream Products

• 674803-10-2 2-N-(4-acetyloxylbenzoyl)-amide-5-chloro-4'-methylsulfonyl-benzophenone 
• 674803-07-7 2-N-(4-methylbenzoyl)-amide-5-chloro-4'-methylsulfonyl-benzophenone 
• 674803-05-5 2-N-(4-chlorobenzoyl)-amide-5-chloro-4'-methylsulfonyl-benzophenone 
• 674803-06-6 2-N-(4-methoxybenzoyl)-amide-5-chloro-4'-methylsulfonyl-benzophenone 
• 674803-08-8 2-N-(2-fluorobenzoyl)-amide-5-chloro-4'-methylsulfonyl-benzophenone 
• 674803-09-9 2-N-(2-acetyloxylbenzoyl)-amide-5-chloro-4'-methylsulfonyl-benzophenone 

Relevant academic research and scientific papers

Sulfonyl-containing 2,3-diarylindole compounds, methods for making same, and methods of use thereof

The present invention relates to sulfonyl-containing 2,3-diarylindole, especially to new compounds of general Formula, to a preparation method for their preparation, to pharmaceutical compositions containing said compound, and to the medical use thereof in the treatment of diseases relating to the inhibition of cyclooxygenase-2 (COX-2).

Discovery of 2-phenyl-3-sulfonylphenyl-indole derivatives as a new class of selective COX-2 inhibitors

2-Sulfonylphenyl-3-phenyl-indole derivatives have been reported to be highly potent and selective COX-2 inhibitors previously. In this paper, the regio-isomeric analogues-2-phenyl-3-sulfonylphenyl-indoles were identified as potent and selective COX-2 inhi