66047-04-9 Usage
Uses
Used in Pharmaceutical Industry:
2,4(1H,3H)-Pyrimidinedione, 5-(3-methylphenoxy)is used as a pharmaceutical compound for its potential role in modulating biological processes. Its specific application reason is due to its ability to interact with various biological targets, which may lead to the development of new therapeutic agents.
Used in Chemical Research:
In the field of chemical research, 2,4(1H,3H)-Pyrimidinedione, 5-(3-methylphenoxy)is used as a research compound for studying its chemical properties, reactivity, and potential applications in the synthesis of other complex molecules. 2,4(1H,3H)-Pyrimidinedione, 5-(3-methylphenoxy)-'s unique structure makes it an interesting candidate for further investigation and development.
Used in Drug Development:
As a derivative of Tolimidone, 2,4(1H,3H)-Pyrimidinedione, 5-(3-methylphenoxy)is used as a potential drug candidate for increasing glucose tolerance in vivo. Its application reason is based on its allosteric activation of Lyn kinase in vitro, which may contribute to improved glucose homeostasis and management of diabetes-related conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 66047-04-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,0,4 and 7 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 66047-04:
(7*6)+(6*6)+(5*0)+(4*4)+(3*7)+(2*0)+(1*4)=119
119 % 10 = 9
So 66047-04-9 is a valid CAS Registry Number.
66047-04-9Relevant articles and documents
Bronchodilator and Antiulcer Phenoxypyrimidinones
Lipinski, C. A.,Stam, J. G.,Pereira, J. N.,Ackerman, N. R.,Hess, H.-J.
, p. 1026 - 1031 (2007/10/02)
Series of 5-phenoxy-2(1H)-pyrimidinones, 5-phenoxy-4(3H)-pyrimidinones, and related compounds were prepared in a follow-up of a lead prepared as a potential cyclic nucleotide regulating agent.Compounds were evaluated for bronchodilator activity in histamine-challenged guinea pigs and for antiulcer activity in a cold-restraint, stressed rat ulcer model.Bronchodilator activity comparable to, or greater than, that of theophylline was found in both the 2(1H)- and 4(3H)-pyrimidinone series and was most prominent in analogues containing either an electron-withdrawing or -donating substituent in the para position of the phenoxy ring.Significant antiulcer activity was observed only in the 2(1H)-pyrimidinone series among three closely related analogues.One of these, 5-(m-methylphenoxy)-2(1H)-pyrimidinone (3), exhibited more potent antiulcer effects than the clinically useful antiulcer agent carbenoxolone, without demonstrating bronchodilator activity.
5-M-Tolyloxyuracil, anti-ulcer agent
-
, (2008/06/13)
5-M-Tolyloxyuracil, in substantially pure form and also in unit dosage form in a pharmaceutically acceptable diluent. Its use in the treatment of peptic ulcer is claimed.
