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5-Fluorouracil glucuronide is a derivative of 5-Fluorouracil (F596010), specifically the N-glucuronide form. Unlike its O-glucuronide analog, it does not exhibit significant antitumor activity.
Usage:
Used in Pharmaceutical Research:
5-Fluorouracil glucuronide is used as a research compound for understanding the differences in activity and properties between N-glucuronide and O-glucuronide derivatives of 5-Fluorouracil. This knowledge can be applied to the development of more effective cancer treatments and the study of drug metabolism and pharmacokinetics.
Used in Drug Metabolism Studies:
5-Fluorouracil glucuronide is used as a model compound in drug metabolism studies to investigate the role of glucuronidation in the biotransformation of drugs. This can help researchers understand how different glucuronide derivatives affect the pharmacological properties and efficacy of drugs.
Used in Quality Control:
5-Fluorouracil glucuronide can be used as a reference material in the quality control of pharmaceutical products containing 5-Fluorouracil or its derivatives. This ensures the accurate measurement and assessment of the active pharmaceutical ingredient in the final product.
Used in Drug Development:
Although 5-Fluorouracil glucuronide does not have significant antitumor activity, it can still be used in the development of new drugs by providing insights into the structure-activity relationship of 5-Fluorouracil and its derivatives. This information can be valuable in designing more potent and selective anticancer agents.
Used in Toxicology Studies:
5-Fluorouracil glucuronide can be employed in toxicology studies to evaluate the safety and potential side effects of 5-Fluorouracil and its derivatives. Understanding the metabolic pathways and toxicological profile of these compounds is crucial for their safe and effective use in clinical settings.

66048-45-1

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66048-45-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 66048-45-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,0,4 and 8 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 66048-45:
(7*6)+(6*6)+(5*0)+(4*4)+(3*8)+(2*4)+(1*5)=131
131 % 10 = 1
So 66048-45-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H11FN2O8/c11-2-1-13(10(20)12-7(2)17)8-5(16)3(14)4(15)6(21-8)9(18)19/h1,3-6,8,14-16H,(H,18,19)(H,12,17,20)/t3-,4-,5+,6-,8+/m0/s1

66048-45-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name N1-(β-D-glucopyranuronosyl)-5-fluorouracil

1.2 Other means of identification

Product number -
Other names 5-Fluorouracil N-Beta-D-Glucuronide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:66048-45-1 SDS

66048-45-1Downstream Products

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