66074-34-8Relevant academic research and scientific papers
Studies on Decarboxylation Reactions. Part 5. Micellar Catalysis and Mixed Solvents Effects on the Decarboxylation of Some N-Alkyl- or N-Aryl-substituted 5-Amino-1,3,4-oxadiazole-2-carboxylic Acids
Noto, Renato,Buscemi, Silvestre,Werber, Giuseppe,Spinelli, Domenico
, p. 1449 - 1452 (2007/10/02)
The effect of micelles and mixed solvents on the decarboxylation of some N-alkyl- or N-aryl-substituted 5-amino-1,3,4-oxadiazole-2-carboxylic acids has been studied.The data support the unimolecular decarboxylation mechanism proposed by us.Moreover, they show that mixed solvents and micelles have different effects on reactivity of the amino acids under study.
Studies on Decarboxylation Reactions. Part 6. Kinetic Study of Decarboxylation of 5-Amino-1,3,4-oxadiazole-2-carboxylic Acid and its N-Phenyl Derivatives at High Hydrochloric Acid Concentrations
Noto, Renato,Werber, Giuseppe,Buccheri, Francesco,Arnone, Caterina
, p. 1457 - 1459 (2007/10/02)
The dissociation constants (K1) of both acids 4a-c and esters 5a-c and the rate constants of the decarboxylation reaction of acids 4a-c have been measured at various high concentrations of hydrochloric acid (0.5-8.0 M range).The results obtained have enabled us to suggest the probable structure of the zwitterion which undergoes decarboxylation.
Studies on Decarboxylation Reactions. Part 4. Kinetic Study of the Decarboxylation of Some N-Alkyl- or N-Phenyl-Substituted 5-Amino-1,3,4-oxadiazole-2-carboxylic Acids
Noto, Renato,Buccheri, Francesco,Consiglio, Giovanni,Spinelli, Domenico
, p. 1627 - 1630 (2007/10/02)
The rate constants of the decarboxylation reaction of compounds (Ib-f) have been measured in water over a range of proton activities, at various temperatures.The results obtained strongly support the unimolecular decarboxyprotonation mechanism.
