6610-05-5Relevant articles and documents
Bimetallic organotin(IV) complexes with ferrocene-based azomethines: Synthesis, characterization, semi-empirical study, and antibacterial activity
Tahira, Khizra,Ali, Saqib,Shahzadi, Saira,Sharma, Saroj K.,Qanungo, Kushal
experimental part, p. 1871 - 1884 (2012/03/22)
A series of bimetallic organotin(IV) complexes with ferrocene-based azomethines (Schiff bases) were synthesized by reacting sodium salt of tranexamic acid, 4-amino butanoic acid, and phenyl alanine with trimethyltin and tributyltin chloride in 1 : 1 molar ratio under inert atmosphere. The synthesized trialkyl organotin complexes condense with formyl ferrocene under inert atmosphere to yield organotin(IV) ferrocenyl Schiff bases. Composition of the organotin(IV) complexes, bonding behavior of donor groups, and structural assignments were studied by elemental analysis, FT-IR, 1H, 13C, 119Sn NMR, and mass spectrometry. The spectral data suggest that the ligand is bidentate, coordinating through oxygens. Spectroscopic techniques reveal distorted tetrahedral geometry in solution for the complexes. As solids, the complexes are trigonal bipyramidal, confirmed by semi-empirical study. Mass spectrometric and elemental analysis data support the solid and solution spectroscopic results. Bioactivity screenings show invitro biological potential.
Competitive intramolecular aminolysis: Relative rates of 5-and 6-membered lactam ring closure
Patterson, Kevin H.,Depree, Gary J.,Zender, Johannes A.,Morris, Peter J.
, p. 281 - 284 (2007/10/02)
Methyl 4,5-diaminopentanoate (4,5-Dape Me) undergoes competitive intramolecular aminolysis to 5-aminomethyl-2-pyrrolidinone (L5) and 5-amino-2-piperidinone (L6) in dilute alkaline aqueous solution at 25°C. Use of this single compound provides an ideal case for assessing the relative rates of 5- and 6-membered lactam ring closure. Assessments are also made using the intramolecular aminolysis of pairs of compounds: methyl 2,4-diaminobutanoate (2,4-Dab Me) and methyl 2,5-diaminopentanoate (2,5-Dape Me); methyl 4-aminobutanoate (4-Ab Me) and methyl 5-aminopentanoate (5-Ape Me).
Studies on absorption promoters for rectal delivery preparations. I. Promoting efficacy of enamine derivatives of amino acid for the rectal absorption of β-lactam antibiotics in rabbits
Murakami,Yata,Tamauchi,Nakai,Yamazaki,Kamada
, p. 1998 - 2004 (2007/10/02)
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