66107-29-7

Basic information

• Product Name: 4-METHOXYPHENYL TRIFLUOROMETHANESULFONATE
• Synonyms: TIMTEC-BB SBB006469;4-METHOXYPHENYL TRIFLUOROMETHANESULFONATE;Trifluoromethanesulfonicacid4-methoxyphenylester;4-METHOXYPHENYL TRIFLUOROMETHANESULFONATE, 97% MIN.;4-Methoxyphenyl trifluoromethanesulphonate;4-Methoxyphenyl triflate;1-(Trifluoromethylsulfonyloxy)-4-methoxybenzene;1-Methoxy-4-(trifluoromethylsulfonyloxy)benzene
• CAS NO: 66107-29-7
• Molecular Formula: C₈H₇F₃O₄S
• Molecular Weight: 256.2
• Mol File: 66107-29-7.mol
• Article Data: 55

Chemical Properties

• Boiling Point: 125°C/18mm
• Flash Point: 113 °C
• Appearance: /
• Density: 1.416
• Vapor Pressure: 0.00526mmHg at 25°C
• Refractive Index: 1.454
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-METHOXYPHENYL TRIFLUOROMETHANESULFONATE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-METHOXYPHENYL TRIFLUOROMETHANESULFONATE(66107-29-7)
• EPA Substance Registry System: 4-METHOXYPHENYL TRIFLUOROMETHANESULFONATE(66107-29-7)

Safety Data

• Hazard Codes: Xi,T
• Statements: 23/24/25-34-40
• Safety Statements: 23-26-36/37/39-45
• RIDADR: UN 3265 8/PG 2
• Hazardous Substances Data: 66107-29-7(Hazardous Substances Data)

Usage

Uses

4-Methoxyphenyl trifluoromethanesulfonate is a useful research chemical.

InChI:InChI=1/C8H7F3O4S/c1-14-6-2-4-7(5-3-6)15-16(12,13)8(9,10)11/h2-5H,1H3

Upstream product

• 358-23-6 trifluoromethylsulfonic anhydride 
• 150-76-5 4-methoxy-phenol 
• 1493-13-6 trifluorormethanesulfonic acid 
• 421-83-0 trifluoromethane sulfonyl chloride 
• 100-66-3 methoxybenzene 
• 37595-74-7 N,N-phenylbistrifluoromethane-sulfonimide 
• 109-72-8 n-butyllithium 
• 17763-80-3 para-nitrophenyl triflate 

Downstream Products

• 140706-14-5 (S)-N-(1-hydroxy-3-methylbutan-2-yl)-4-methoxybenzamide 
• 132165-61-8 (Z)-methyl 2-acetamido-3-(4-methoxyphenyl)acrylate 
• 56982-37-7 4-[(4-methoxyphenyl)ethynyl]benzonitrile 
• 150-76-5 4-methoxy-phenol 
• 100-09-4 4-methoxybenzoic acid 
• 129887-49-6 (E)-2-(4-methoxyphenyl)but-2-en-1-ol 
• 3989-14-8 (4-methoxyphenylethynyl)trimethylsilane 
• 131516-15-9 (-)-(S)-2-(4-methoxyphenyl)-2,5-dihydrofuran 
• 296788-33-5 (+)-(R)-2-(4-methoxyphenyl)-2,5-dihydrofuran 
• 156098-16-7 triisopropyl-(4-methoxyphenylsulfanyl)-silane 
• 213596-33-9 2-(4-methoxyphenyl)-5,5-dimethyl-1,3,2-dioxaborolane 
• 104-94-9 4-methoxy-aniline 
• 2749-94-2 1-methoxy-4-(prop-1-yn-1-yl)benzene 
• 900503-37-9 3-(4-methoxyphenyl)-8-azabicyclo[3.2.1]oct-2-ene-8-carboxylic acid tert-butyl ester 

Relevant articles and documents

Palladium-Catalyzed Reductive Carbonylation of (Hetero) Aryl Halides and Triflates Using Cobalt Carbonyl as CO Source

An efficient protocol for the reductive carbonylation of (hetero) aryl halides and triflates under CO gas-free conditions using Pd/Co2(CO)8 and triethylsilane has been developed. The mild reaction conditions, enhanced chemoselectivity and, easy access to heterocyclic and vinyl carboxaldehydes highlights its importance in organic synthesis.

Dual Photoredox-/Palladium-Catalyzed Cross-Electrophile Couplings of Polyfluoroarenes with Aryl Halides and Triflates

A visible-light photoredox-/Pd-catalyzed cross-electrophile arylation of polyfluoroarenes with aryl halides and triflates in the presence of dialkylamines is reported for the first time. This synergistic protocol affords access to a series of fluorodiaryls from easily available starting materials under mild and operationally simple conditions. A series of mechanistic experiments, including the stoichiometric reactions of a ligated (aryl)Pd complex, Stern-Volmer fluorescence quenching studies, cyclic voltammetry studies, and UV-vis spectroscopy, were performed to elucidate the potential catalytic pathway in this synergistic process.

Ni-Catalyzed Cross-Electrophile Coupling of Aryl Triflates with Thiocarbonates via C-O/C-O Bond Cleavage

A nickel-catalyzed reductive coupling of aryl triflates with thiocarbonates is reported here. Both electron-rich and -deficient aryl C(sp2)-O electrophiles as well as a class of O-tBu S-alkyl thiocarbonates are compatible with the optimized reaction conditions, as evidenced by 49 examples. The reaction also proceeds with good chemoselective cleavage of the C-O bond with regard to thioesters. This work broadens the scope of nickel-catalyzed reductive cross-electrophile coupling reactions.