661452-50-2

Upstream product

• 354563-68-1 1-[4-(1,1-diphenyl-methyl)-piperazin-1-yl]-1-[(S)-1-(4-fluoro-benzyl)-piperidin-2-yl]-methanone 
• 354564-11-7 {4-[Bis-(4-fluoro-phenyl)-methyl]-piperazin-1-yl}-(2S)-piperidin-2-yl-methanone 
• 7051-34-5 cyclopropylcarbinyl bromide 

Relevant academic research and scientific papers

Modulators of the cholesterol biosynthetic pathway

The present invention relates to methods for modulating the cholesterol biosynthetic pathway. The level of cholesterol in the body is linked to numerous pathological states. The methods of the present invention alter the transcription levels of genes involved in the cholesterol biosynthesis. The methods of the present invention can used for treating diseases mediated by the cholesterol biosynthetic pathway.