661467-06-7

Upstream product

• 622-24-2 2-phenylethyl chloride 
• 3150-15-0 methyl 2,3-anhydro-4,6-O-benzilidene-α-D-mannopyranoside 

Downstream Products

• 871917-15-6 Benzoic acid (1R,2S,3S)-3-hydroxy-2-phenethyl-4-(toluene-4-sulfonyloxy)-1-vinyl-butyl ester 
• 871917-13-4 (3R,4S,5R)-3,5-bis-(tert-butyldimethylsilyloxy)-4-(2-phenylethyl)oct-1-en-7-yne 
• 871917-12-3 Benzoic acid (1R,2S,3R)-3-hydroxy-2-phenethyl-6-trimethylsilanyl-1-vinyl-hex-5-ynyl ester 
• 871917-10-1 Benzoic acid (1R,2S,3S)-3,4-dihydroxy-2-phenethyl-1-vinyl-butyl ester 
• 871917-11-2 Benzoic acid (1R,2R)-2-(S)-oxiranyl-4-phenyl-1-vinyl-butyl ester 
• 871917-17-8 (3R,4S,5R)-4-(2-phenylethyl)oct-1-en-7-yne-3,5-diol 
• 871917-08-7 methyl 4-O-benzoyl-6-bromo-3,6-dideoxy-3-(2-phenylethyl)-α-D-altropyranoside 

Relevant academic research and scientific papers

Synthesis of A-ring synthon of 2α-substituted vitamin d3 analogues utilizing Grignard reaction towards methyl 2,3-anhydro-4,6-o-benzylidene-α-D-manno-pyranoside

A concise route to the Trost A-ring precursor enyne for synthesizing 2α-substituted 1α,25-dihydroxyvitamin D3 (1) is described, in which the 2α-substituents could be introduced via addition reaction of Grignard reagent towards the sugar epoxide