66147-03-3Relevant academic research and scientific papers
Iodine scanning of a phenazine inhibitor of vacuolar sorting
Surpin, Marci,Zou, Yunfan,Xiong, Chiyi,Raikhel, Natasha V.,Pirrung, Michael C.
scheme or table, p. 1496 - 1499 (2010/06/19)
Affinity reagents are often used to address the target identification problem in chemical genetics. The design of such reagents so that the linker does not occlude interactions with protein targets is an ongoing challenge. This work describes a systematic approach to synthesize derivatives of a bioactive that should avoid interference with binding to targets and be readily converted to affinity reagents.
