661479-01-2Relevant academic research and scientific papers
Heterogeneous foldamers containing alpha, beta, and/or gamma-amino acids
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, (2008/06/13)
Disclosed are isolated, unnatural polypeptides containing cyclically-constrained β-amino acid residues and cyclically-constrained γ-amino acid residues. The compounds are unnatural and because they contain rotationally constrained residues that are not amenable to enzymatic degradation, the compounds are useful to probe protein-protein and other large molecule interactions.
