66165-42-2

Upstream product

• 110-91-8 morpholine 
• 1148-11-4 N-Benzyloxycarbonyl-L-proline 
• 137862-18-1 (S)-Pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 2-(1-methylene-pentyl) ester 
• 105414-01-5 Cbz-L-Pro-OCO₂-i-Bu 

Downstream Products

• 91790-91-9 (S)-4-[(2-pyrrolidinyl)methyl]morpholine 
• 73094-26-5 morpholino(pyrrolidin-2-yl)methanone 

Relevant academic research and scientific papers

One-pot enantioselective synthesis of 3-nitro-2H-chromenes catalyzed by a simple 4-hydroxyprolinamide with 4-nitrophenol as cocatalyst

The asymmetric domino oxa-Michael-Henry reaction of salicylaldehyde derivatives with trans-β-nitro olefins catalyzed by a readily available trans-4-hydroxy-L-prolinamide with 4-nitrophenol as an effective cocatalyst is presented. The corresponding 3-nitro

Amino acids and peptides. XVI. Synthesis of N-terminal tetrapeptide analogs of fibrin α-chain and their inhibitory effects on fibrinogen/thrombin clotting

N-Terminal tetrapeptide analogs of fibrin α-chain were synthesized by the solution method using a new active ester, the ester of the oxime of p-nitroacetophenone, and by the solid-phase method. Their inhibitory effects on fibrinogen/thrombin clotting were examined. Of the synthetic peptides, amide analogs of Gly-Pro-Arg-Pro exhibited a more potent inhibitory effect.

Enol esters as intermediates for the facile conversion of amino acids into amides and dipeptides

N-Protected amino enol esters are easily transformed at room temperature into amino amides, and in the presence of potassium cyanide as catalyst, into tertiary amides and dipeptides.