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66177-32-0

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66177-32-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 66177-32-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,1,7 and 7 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 66177-32:
(7*6)+(6*6)+(5*1)+(4*7)+(3*7)+(2*3)+(1*2)=140
140 % 10 = 0
So 66177-32-0 is a valid CAS Registry Number.

66177-32-0Downstream Products

66177-32-0Relevant articles and documents

Novel HIV reverse transcriptase inhibitors

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Page/Page column 35-36, (2008/06/13)

The invention is related to compounds of Formula (I), (II), or (III): or a pharmaceutically acceptable salt, solvate, ester, and/or phosphonate thereof, compositions containing such compounds, and therapeutic methods that include the administration of such compounds.

Synthesis and potent tumour necrosis factor-α production inhibitory activity of N-pyridinylphthalimides and derivatives

Collin,Robert,Robert-Piessard,Le Baut,Bobin-Dubigeon,Vernhet,Lang,Petit

, p. 27 - 31 (2007/10/03)

A series of N-azaaryl(alkyl)phthalimides incorporating amino(alkyl)pyridines were synthesized and tested as inhibitors of TNF-α production. The most potent compounds were N-(4,6-dimethyl-pyridin-2-yl)tetrafluorophthalimide (8, 40% inhibition at 10 μM), N-(3-methylpyridinyl)-5-fluorophthalimide (12, 48%) and N-(3-methylpyridinyl)tetrafluorophthalimide (13, 68%). The analogues without (tetra)fluorine substitution on the aromatic ring were less active inhibitors.

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