5β-Pregnan-12α-ol, also known as pregnanolone, is a naturally occurring steroid hormone and a metabolite of progesterone. It plays a crucial role in the central nervous system, acting as a potent neurosteroid with anxiolytic, sedative, and anticonvulsant properties. 5β-pregnan-12α-ol is an allosteric modulator of the GABAA receptor, enhancing its function and leading to increased chloride ion influx, which results in neuronal hyperpolarization and reduced neuronal excitability. Pregnanolone is synthesized in the brain and has been implicated in various physiological processes, including stress response, mood regulation, and sleep. Its therapeutic potential is being explored for the treatment of neurological and psychiatric disorders, such as anxiety, depression, and epilepsy.

6618-40-2

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Basic information
1. Product Name: 5β-pregnan-12α-ol
2. Synonyms:
3. CAS NO:6618-40-2
4. Molecular Formula:
5. Molecular Weight: 304.516
6. EINECS: N/A
7. Product Categories: N/A
Chemical Properties
1. Melting Point: N/A
2. Boiling Point: N/A
3. Flash Point: N/A
4. Appearance: N/A
5. Density: N/A
6. Refractive Index: N/A
7. Storage Temp.: N/A
8. Solubility: N/A
9. CAS DataBase Reference: 5β-pregnan-12α-ol(CAS DataBase Reference)
10. NIST Chemistry Reference: 5β-pregnan-12α-ol(6618-40-2)
11. EPA Substance Registry System: 5β-pregnan-12α-ol(6618-40-2)
Safety Data
1. Hazard Codes: N/A
2. Statements: N/A
3. Safety Statements: N/A
4. WGK Germany:
5. RTECS:
6. HazardClass: N/A
7. PackingGroup: N/A
8. Hazardous Substances Data: 6618-40-2(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 6618-40-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,6,1 and 8 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 6618-40:
(6*6)+(5*6)+(4*1)+(3*8)+(2*4)+(1*0)=102
102 % 10 = 2
So 6618-40-2 is a valid CAS Registry Number.

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