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Δ16-androstene, also known as 16-dehydrotestosterone, is a naturally occurring steroid hormone derived from testosterone. It is characterized by the presence of a double bond at the 16th carbon position in its molecular structure. Δ16-androstene plays a significant role in the biosynthesis of various androgens and estrogens, which are essential for the development and maintenance of male and female sexual characteristics, respectively. Δ16-androstene is also involved in the regulation of the hypothalamic-pituitary-gonadal axis, which controls the production of sex hormones. Due to its anabolic properties, it has been studied for its potential therapeutic applications in conditions such as muscle wasting and osteoporosis. However, it is important to note that the use of Δ16-androstene as a performance-enhancing drug is prohibited in sports due to its potential health risks and ethical concerns.

6618-43-5

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6618-43-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 6618-43-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,6,1 and 8 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 6618-43:
(6*6)+(5*6)+(4*1)+(3*8)+(2*4)+(1*3)=105
105 % 10 = 5
So 6618-43-5 is a valid CAS Registry Number.

6618-43-5Relevant academic research and scientific papers

Steroidal alkenylphosphonates via palladium-catalyzed coupling reactions

Skoda-Foeldes, Rita,Kollar, Laszlo,Horvath, Judit,Tuba, Zoltan

, p. 791 - 795 (1995)

The palladium-catalyzed coupling of various 17-iodo-Δ16 steroids (17-iodo-androst-16-ene, 17-iodo-4-methyl-4-aza-androst-16-en-3-one, and 17-iodo-4-aza-androst-16-en-3-one) with dialkyl phosphites (dimethyl phosphite, diethyl phosphite, and diisopropyl phosphite) was examined in detail.The only successful condition for homogeneous coupling involved carrying out the reaction in the absence of any solvents.A large excess of dialkyl phosphite was used, which means that the phosphite itself acted as a solvent.Eight new androst-16-ene derivatives with phosphonate groups at C-17 were synthesized and characterized.These steroids are of pharmacological interest as potential 5α-reductase inhibitors.Under the same conditions, methylation of lactam NH was observed using dimethyl phosphite. - Keywords: coupling reaction of steroids; steroidal alkenylphosphonates; homogeneous palladium(0) catalysts

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