66184-01-8

Upstream product

• 2789-88-0 1,2-bis(4-methylphenyl)acetylene 
• 71-43-2 benzene 
• 98-80-6 phenylboronic acid 
• 873-55-2 sodium benzenesulfonate 
• 100-58-3 phenylmagnesium bromide 
• 624-31-7 4-tolyl iodide 
• 766-97-2 4-n-methylphenylacetylene 
• 591-51-5 phenyllithium 
• 150177-33-6 (Z)-(1-phenylethene-1,2-diyl)bis(trimethylgermane) 
• 536-74-3 phenylacetylene 

Relevant academic research and scientific papers

Synthesis of vinylgermanes via the Au/TiO2-catalyzed cis-1,2-digermylation of alkynes and the regioselective hydrogermylation of allenes

In the presence of Au/TiO2 (1 mol %), terminal alkynes react quantitatively with stoichiometric amounts of the unactivated digermane Me3Ge-GeMe3, forming exclusively cis-1,2-digermylated alkenes. We also establish the Au/TiO2-catalyzed hydrogermylation of terminal allenes with Et3GeH, which exhibits a highly regioselective mode of addition on the more substituted double bond forming vinylgermanes. Additionally, we provide preliminary results regarding the Pd nanoparticle-catalyzed C-C coupling of 1,2-digermyl alkenes with aryl iodides.

Palladium-Catalyzed C?H Alkenylation of Arenes with Alkynes: Stereoselective Synthesis of Vinyl Chlorides via a 1,4-Chlorine Migration

A directing group-free, ligand-promoted palladium-catalyzed C?H arylation of internal alkynes with simple arenes was developed. Alkenyl chlorides resulting from a 1,4-chlorine migration or trisubstituted alkenes were produced in moderate to good yields depending on the type of alkyne.

Zirconoarylation of alkynes through p-chloranilpromoted reductive elimination of arylzirconates

A novel method for the zirconoarylation of alkynes was developed. TCQ-promoted reductive elimination of arylzirconate [LiCp2ZrAr(RC=CR) ], which was prepared by the reaction of zirconocene-alkyne complexes with aryllithium compounds, afforded trisubstituted alkenylzirconocenes. This reaction can afford multi-substituted olefins with high stereoselectivity.

Ambient arylmagnesiation of alkynes catalysed by ligandless nickel(ii)

A simple and efficient catalytic arylmagnesiation of diarylacetylenes and aryl(alkyl)acetylenes is accomplished by NiCl2·6H2O at r.t. in the absence of stabilising ligands. The corresponding tetra-substituted alkenes can be obtained in good yields by subsequent treatment with different electrophiles. The Royal Society of Chemistry 2013.

Palladium-catalyzed desulfitative hydroarylation of alkynes with sodium sulfinates

A palladium-catalyzed desulfitative hydroarylation of alkynes with aryl sulfinic acid sodium salts is described. The reaction showed good regio- and stereoselectivity, and afforded the hydroarylation products in good yields. Various functional groups were well tolerated under the optimized reaction conditions.

Palladium-catalyzed hydroarylation of alkynes with arylboronic acids

Reaction of symmetrical and unsymmetrical alkynes with arylboronic acids, using PdCl2 as catalyst source and i-Pr2NPPh2 as ligand, afforded trisubstituted alkenes with regioselectivity in good to excellent yields without a common additional acetic acid. Its efficiency has been demonstrated by its good functional groups, high yield and crowded substrates.

Phosphine-free rhodium-catalyzed hydroarylation of diaryl acetylenes with boronic acids

Rh(CO)2(acac) was found to be an efficient and simple catalyst in hydroarylation of diaryl acetylenes with boronic acids in the absence of phosphine ligand. Thus, triaryl-substituted olefins were prepared in good to excellent yields. No 1,4-rho