66191-03-5Relevant academic research and scientific papers
Acylphosphonates. 4. Synthesis of Dithymidine Phosphonate: A New Method for Generation of Phosphonate Function via Aroylphosphonate Intermediates
Kume, Akiko,Fujii, Mitsuo,Sekine, Mitsuo,Hata, Tsujiaki
, p. 2139 - 2143 (1984)
Dithymidine phosphonate (10) was synthesized by a new method via dithymidine aroylphosphonates (3) in which the aroyl group served as a protecting group for O=P-H functions.In a way analogous to the phosphotriester method, 3 was prepared by successive con
Compositions comprising oxophosphonate-based metalloproteinase inhibitors
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Page/Page column 13, (2008/06/13)
The present invention relates to compositions useful for treating or controlling disease states or conditions associated with zinc containing proteinases, especially metalloproteinases. The active ingredient in these compositions is an alpha-oxo- or alpha
