66202-97-9 Usage
Chemical structure
A complex chemical compound consisting of a benzofuran ring with two methoxy groups, a piperidine ring, an ethyl group, and a urea moiety.
Molecular weight
Approximately 392.47 g/mol
Appearance
Likely a solid or crystalline substance, though specific appearance may vary depending on the conditions.
Solubility
The solubility of 1-[4,7-dimethoxy-6-(2-piperidin-1-ylethoxy)-1-benzofuran-5-yl]-3-ethylurea is not explicitly mentioned, but it may be soluble in organic solvents such as ethanol, methanol, or dimethyl sulfoxide (DMSO) due to its nonpolar nature.
Stability
The stability of 1-[4,7-dimethoxy-6-(2-piperidin-1-ylethoxy)-1-benzofuran-5-yl]-3-ethylurea is not explicitly mentioned, but it may be sensitive to light, heat, or moisture, as many organic compounds with multiple functional groups are.
Pharmacological or biological activity
Likely has specific pharmacological or biological activity due to its complex structure, which may be relevant in medicinal chemistry or pharmaceutical research.
Handling precautions
It is important to handle this chemical with care, as it may have potential hazards or require specific storage conditions. It is also essential to understand its properties before utilization.
Applications
Potential applications in medicinal chemistry or pharmaceutical research, possibly as a drug candidate or a chemical probe for studying biological processes.
Safety
As with any chemical compound, it is crucial to follow proper safety protocols when handling, storing, and using 1-[4,7-dimethoxy-6-(2-piperidin-1-ylethoxy)-1-benzofuran-5-yl]-3-ethylurea, including wearing appropriate personal protective equipment (PPE) and working in a well-ventilated area.
Check Digit Verification of cas no
The CAS Registry Mumber 66202-97-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,2,0 and 2 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 66202-97:
(7*6)+(6*6)+(5*2)+(4*0)+(3*2)+(2*9)+(1*7)=119
119 % 10 = 9
So 66202-97-9 is a valid CAS Registry Number.
66202-97-9Relevant academic research and scientific papers
Synthesis and Antiarrhythmic Activity of New Benzofuran Derivatives
Bourgery, Guy,Dostert, Philippe,Lacour, Alain,Langlois, Michel,Pourrias, Bernard,Tisne-Versailles, Jacky
, p. 159 - 167 (2007/10/02)
Various 5-aminobenzofuran derivatives were prepared from khellin and screened intravenously in the dog for their potential antiarrhythmic activity against ouabain-induced ventricular arrhythmia and in the Harris test.From systematic structural variations it was found that two methoxy groups in positions 4 and 7 on the benzofuran ring, a tertiary aminoethoxy side chain in position 6, and a N-methylurea group in position 5 led to the most active compounds.These were then tested orally in the Harris test in the dog.The two long-acting derivativesN--N'-methylurea (8j) and N--N'-methylurea (8m) showed advantages when compared to quinidine and diisopyramide and have been selected for further studies.
