66203-01-8 Usage
Chemical structure
A complex chemical compound with a benzofuran ring and a urea functional group.
2-azepan-1-ylethoxy
A seven-membered nitrogen-containing ring attached to the benzofuran ring.
Two methoxy groups
Attached to the benzofuran ring, providing additional functionality and steric hindrance.
Methyl group
A methyl group is attached to the urea moiety, which can influence the compound's reactivity and properties.
Potential applications
The compound has potential applications in the field of medicinal chemistry due to its unique structure.
Pharmacological properties
Further research is needed to explore the potential uses and effects of this chemical compound, as it may possess pharmacological properties.
Research focus
The compound's potential as a therapeutic agent or lead compound in drug discovery requires further investigation to understand its biological activity and mechanism of action.
Synthesis
The synthesis of this complex molecule may involve multiple steps, including the formation of the benzofuran ring, introduction of the urea functional group, and attachment of the various substituents.
Stability
The stability of the compound under various conditions (e.g., temperature, pH, etc.) should be investigated to determine its suitability for pharmaceutical applications.
Solubility
The solubility of the compound in different solvents may impact its formulation and delivery in potential medicinal applications.
Toxicity
The compound's toxicity profile should be assessed to ensure its safety for use in medicinal applications.
Structural analogs
Investigating structural analogs of 1-[6-(2-azepan-1-ylethoxy)-4,7-dimethoxy-1-benzofuran-5-yl]-3-methylurea may provide insights into the structure-activity relationship and help optimize the compound for specific applications.
Patentability
The compound's unique structure may be patentable, providing intellectual property protection for its development and commercialization in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 66203-01-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,2,0 and 3 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 66203-01:
(7*6)+(6*6)+(5*2)+(4*0)+(3*3)+(2*0)+(1*1)=98
98 % 10 = 8
So 66203-01-8 is a valid CAS Registry Number.
66203-01-8Relevant academic research and scientific papers
Synthesis and Antiarrhythmic Activity of New Benzofuran Derivatives
Bourgery, Guy,Dostert, Philippe,Lacour, Alain,Langlois, Michel,Pourrias, Bernard,Tisne-Versailles, Jacky
, p. 159 - 167 (2007/10/02)
Various 5-aminobenzofuran derivatives were prepared from khellin and screened intravenously in the dog for their potential antiarrhythmic activity against ouabain-induced ventricular arrhythmia and in the Harris test.From systematic structural variations it was found that two methoxy groups in positions 4 and 7 on the benzofuran ring, a tertiary aminoethoxy side chain in position 6, and a N-methylurea group in position 5 led to the most active compounds.These were then tested orally in the Harris test in the dog.The two long-acting derivativesN--N'-methylurea (8j) and N--N'-methylurea (8m) showed advantages when compared to quinidine and diisopyramide and have been selected for further studies.
