662142-96-3Relevant academic research and scientific papers
Direct asymmetric aldol reactions in water with a β-aminosulfonamide organocatalyst
Miura, Tsuyoshi,Ina, Mariko,Imai, Kie,Nakashima, Kosuke,Yasaku, Yumi,Koyata, Naka,Murakami, Yasuoki,Imai, Nobuyuki,Tada, Norihiro,Itoh, Akichika
experimental part, p. 1028 - 1034 (2011/09/20)
Organocatalyst 4 promoted the direct asymmetric aldol reactions of aldehydes with ketones in brine or in the presence of water to afford the corresponding anti-aldol products in moderate to excellent yields with up to 97% ee.
Direct asymmetric aldol reactions in brine using novel sulfonamide catalyst
Miura, Tsuyoshi,Yasaku, Yumi,Koyata, Naka,Murakami, Yasuoki,Imai, Nobuyuki
scheme or table, p. 2632 - 2635 (2009/08/09)
Direct asymmetric aldol reactions of aldehydes with ketones in the presence of a catalytic amount of sulfonamide 4 and trifluoroacetic acid afforded the corresponding anti-aldol products in moderate to excellent yields with 85-93% ee.
