662159-99-1

Upstream product

• 135857-20-4 2-(4-formyl-phenoxy)-acetamide 
• 109-77-3 malononitrile 

Downstream Products

• 335208-79-2 2-[4-(1-amino-2,4-dicyanopyrido[1,2-a]benzimidazol-3-yl)phenoxy]acetamide 
• 1314881-63-4 2-(4-(1-amino-6-chloro-2,4-dicyanobenzo[4,5]imidazo[1,2-a]pyridin-3-yl)phenoxy)acetamide 
• 1314881-64-5 2-(4-(1-amino-2,4-dicyano-6-methoxybenzo[4,5]imidazo[1,2-a]pyridin-3-yl)phenoxy)acetamide 
• 1314881-65-6 2-(4-(1-amino-2,4-dicyano-6,7-dimethylbenzo[4,5]imidazo[1,2-a]pyridin-3-yl)phenoxy)acetamide 
• 1314881-66-7 2-(4-(1-amino-2,4-dicyano-7,8-dimethylbenzo[4,5]imidazo[1,2-a]pyridin-3-yl)phenoxy)acetamide 
• 1314881-62-3 2-(4-(1-amino-2,4-dicyano-6-methylbenzo[4,5]imidazo[1,2-a]pyridin-3-yl)phenoxy)acetamide 

Relevant academic research and scientific papers

Inhibition of the cellular function of perforin by 1-amino-2,4- dicyanopyrido[1,2-a]benzimidazoles

A high throughput screen showed the ability of a 1-amino-2,4- dicyanopyrido[1,2-a]benzimidazole analogue to directly inhibit the lytic activity of the pore-forming protein perforin. A series of analogues were prepared to study structure-activity relations