66217-03-6Relevant academic research and scientific papers
An improved method for the regiospecific synthesis of polysubstituted [2.2]paracyclophanes
Chow, Hak-Fun,Low, Kam-Hung,Wong, King Y.
, p. 2130 - 2134 (2005)
4,16-Disubstituted, 4,7,12,15-tetrasubstituted, 4,8,12,16-tetrasubstituted and 4,5,7,8,12,13,15,16-octasubstituted [2.2]paracyclophanes can be prepared in significantly improved yields and excellent regiospecificities via the Winberg 1,6-elimination-dimerization reaction from substituted (4-methylbenzyl) trimethylammonium hydroxides. Using 2-chloro-phenothiazine instead of phenothiazine as a polymerization inhibitor results in a doubling of product yields. Georg Thieme Verlag Stuttgart.
