6622-61-3Relevant academic research and scientific papers
Synthesis and selective cytotoxic activities on rhabdomyosarcoma and noncancerous cells of some heterocyclic chalcones
Do, Tuong-Ha,Nguyen, Dai-Minh,Truong, Van-Dat,Do, Thi-Hong-Tuoi,Le, Minh-Tri,Pham, Thanh-Quan,Thai, Khac-Minh,Tran, Thanh-Dao
, (2016/04/20)
Chemically diverse heterocyclic chalcones were prepared and evaluated for cytotoxicity, aiming to push forward potency and selectivity. They were tested against rhabdomyosarcoma (RMS) and noncancerous cell line (LLC-PK1). The influence of heteroaryl patte
SUBSTITUTED CHROMANES AND METHOD OF USE
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Page/Page column 144, (2016/05/19)
The invention provides for compounds of formula (I), wherein R1, X, Y, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, R14, m, and R" have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions mediated and modulated by CFTR, including cystic fibrosis, Sj?gren's syndrome, pancreatic insufficiency, chronic obstructive lung disease, and chronic obstructive airway disease. Also provided are pharmaceutical compositions comprised of one or more compounds of formula (I).
