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(2E)-1-(5-chloro-2-hydroxyphenyl)-3-(2,4-dichlorophenyl)prop-2-en-1-one, also known as Clodinafop-propargyl, is a chemical compound that belongs to the class of aryloxyphenoxypropionate herbicides. It is primarily used as an herbicide to control annual and perennial grass weeds in various crops.
Used in Agriculture:
Clodinafop-propargyl is used as an herbicide for controlling annual and perennial grass weeds in crops such as wheat, barley, and rice. It works by inhibiting the acetyl coenzyme A carboxylase (ACCase) enzyme in target plants, leading to a disruption in lipid synthesis and subsequent plant death. It is important to handle and use Clodinafop-propargyl with care, following safety guidelines and regulations to minimize environmental and human health risks.

6623-08-1

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6623-08-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 6623-08-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,6,2 and 3 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 6623-08:
(6*6)+(5*6)+(4*2)+(3*3)+(2*0)+(1*8)=91
91 % 10 = 1
So 6623-08-1 is a valid CAS Registry Number.

6623-08-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name (E)-1-(5-chloro-2-hydroxyphenyl)-3-(2,4-dichlorophenyl)prop-2-en-1-one

1.2 Other means of identification

Product number -
Other names 2,4,5'-trichloro-2'-hydroxychalcone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6623-08-1 SDS

6623-08-1Downstream Products

6623-08-1Relevant academic research and scientific papers

Biological evaluation of synthetic analogues of curcumin: Chloro-substituted-20-hydroxychalcones as potential inhibitors of tubulin polymerization and cell proliferation

Aryapour, Hassan,Riazi, Gholam Hossein,Foroumadi, Alireza,Ahmadian, Shahin,Shafiee, Abbas,Karima, Oveis,Mahdavi, Majid,Emami, Saeed,Sorkhi, Maedeh,Khodadady, Sirus

experimental part, p. 503 - 510 (2012/04/11)

A series of chloro-substituted-20-hydroxychalcones were prepared and evaluated for their cytotoxic effects against K562 and SK-N-MC human cancer cell lines and as the inhibitors of tubulin polymerization. The 3,50-dichloro- analogue (compound 3) inhibited the assembly of protofilaments with 89% inhibition. Compound 3 was found to be bound to tubulin with a dissociation constant of 3.7 lM and altered far-UV circular dichroism spectrum of tubulin and altered far-UV circular dichroism spectrum of tubulin.

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