66232-56-2

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
2-Amino-6-ethylbenzoic acid serves as a fundamental building block in the synthesis of various pharmaceutical and agrochemical compounds. Its unique structure allows for the development of new drugs with potential therapeutic benefits.
Used in Drug Development:
Owing to its potential anti-inflammatory and analgesic properties, 2-amino-6-ethylbenzoic acid is of interest in the research and development of novel medications aimed at treating pain and inflammation.
Used in Dye and Pigment Manufacturing:
Beyond its pharmaceutical applications, 2-amino-6-ethylbenzoic acid is also utilized in the production of certain dyes and pigments, highlighting its versatility in different industrial applications.

InChI:InChI=1/C9H11NO2/c1-2-6-4-3-5-7(10)8(6)9(11)12/h3-5H,2,10H2,1H3,(H,11,12)

Upstream product

• 34934-05-9 4-Ethyl-1H-indole-2,3-dione 
• 13619-70-0 2-acetyl-6-nitrobenzoic acid 
• 148843-77-0 7-amino-3-methyl-2-benzofuran-1(3H)-one 
• 13619-67-5 7-amino-3-hydroxy-3-methylisobenzofuran-1(3H)-one 

Downstream Products

• 248282-01-1 N-ethyl-N-phenyl-1,2-dihydro-4-hydroxy-5-ethyl-1-methyl-2-oxo-quinoline-3-carboxamide 

Relevant academic research and scientific papers

Preparation method of 2-amino-6-ethylbenzoic acid and intermediate of 2-amino-6-ethylbenzoic acid

The invention discloses a preparation method of 2-amino-6-ethylbenzoic acid and an intermediate of 2-amino-6-ethylbenzoic acid. The preparation method comprises the following steps: carrying out catalytic hydrogenation on fatty amine salt of a compound II

Concise Synthesis of Key Intermediates of Pyriftalid and Paquinimod via Hydrogenation Method

An efficient and scalable synthesis of 7-amino-3-methylisobenzofuran-1(3H)-one (1) and 2-amino-6-ethylbenzoic acid (2) has been developed via a one-step catalytic hydrogenation. The triethylammonium salt of 2-acetyl-6-nitrobenzoic acid was used as the sta

Development and evaluation of a non-peptidic ligand for the molecular imaging of inflammatory processes using S100A9 (MRP14) as a novel target

The establishment of novel molecular imaging tools to monitor the local activity of inflammation remains an interdisciplinary challenge. Our target, the alarmin S100A9, one subunit of the heterodimer S100A8/S100A9 (calprotectin), is locally secreted in hi

Method for the preparation of 2-amino-6-ethylbenzoic acid

The present invention relates to a novel method for the production of 2-amino-6-ethylbenzoic acid wherein 7-amino-3-methylphtalide or 7-amino-3-hydroxy-3-methylphtalide is reduced to 2-amino-6-ethylbenzoic acid in water or in a mixture of a water miscible

METHOD FOR THE PREPARATION OF 2-AMINO-6-ETHYLBENZOIC ACID

The present invention relates to a novel method for the production of 2- amino-6-ethylbenzoic acid wherein7-amino-3-methylphtalide or 7-amino-3- hydroxy-3-methylphtalide is reduced to 2-amino-6-ethylbenzoic acid in water or in a mixture of a water miscibl

Synthesis and optimization of 2-pyridin-3-yl-benzo[d][1,3]oxazin-4-one based inhibitors of human neutrophil elastase

The hit-to-lead optimization of the HNE inhibitor 5-methyl-2-(2-phenoxy-pyridin-3-yl)-benzo[d][1,3]oxazin-4-one is described. A structure-activity relationship study that focused on the 5 and 7 benzoxazinone positions yielded the optimized 5-ethyl-7-metho

7-(4,6-dimethoxypyrimidinyl)oxy- and -thiophthalides as novel herbicides: Part 1. CGA 279 233: A new grass-killer for rice

A series of novel types of 7-(4,6-dimethoxypyrimidin-2-yl)oxy - and -thio-3-methyl-1 (3H)-isobenzofuranones were discovered at Dr R Maag AG. From the thio-isobenzofuranyl series, CGA 279 233 - BSI-proposed common name pyriftalid - was chosen for further development as a grass herbicide for use in rice. General synthetic approaches to these new phthalic acid-derived compounds are given, with emphasis on the synthesis of pyriftalid and its physico-chemical behaviour.

4H-3,1-BENZOXAZIN-4-ONES AND RELATED COMPOUNDS AND USE AS ENZYME INHIBITORS

Novel 2-amino-4H-3,1-benzoxazin-4-ones represented by the formula wherein R 1, R 2, R 3 and X are defined herein are useful as enzyme inhibitors in animals.

2-OXY-4H-3,1-BENZOXAZIN-4-ONES AND PHARMACEUTICAL USE

2-Oxy-4H-3,1-benzoxazin-4-ones represented by the formula: STR1 and the pharmaceutically acceptable acid addition salts thereof, wherein: a is an integer of 0-4;A is a bond, or alkylene having one to eight carbon atoms;R is hydrogen, phenyl, imidazolyl or cycloalkyl having three to six carbon atoms, wherein the phenyl, imidazolyl or cycloalkyl ring is optionally substituted with 1-3 substituents independently selected from the group consisting of lower alkyl having one to four carbon atoms, lower alkoxy having one to four carbon atoms,--N(R 1) 2,--NO 2, halo or lower alkylthio having one to four carbon atoms, and, each R' is independently selected from the group consisting of lower alkyl having one to six atoms, lower alkenyl having two to six carbon atoms, lower alkoxy having one to six carbon atoms, lower alkylthio or halo-lower alkyl having one to four carbon atoms, halo,--NO 2,--N(R 1) 2, STR2--NR 1 COR 2, and STR3 in which each R 1 is independently hydrogen or lower alkyl having one to four carbon atoms, or together form a piperidine or a piperazine ring optionally substituted at the ring nitrogen by lower alkyl having one to four carbon atoms or--CH 2 CH 2 OH, each R 2 is independently lower alkyl having one to four carbon atoms, A is an alkylene group if R is hydrogen, and the pharmaceutically acceptable acid addition salts thereof are useful as serine protease inhibitors in humans and animals.