66241-39-2Relevant academic research and scientific papers
Iridium-catalyzed 1,3-hydrogen shift/chlorination of allylic alcohols
Ahlsten, Nanna,Gomez, Antonio Bermejo,Martin-Matute, Belen
supporting information, p. 6273 - 6276 (2013/07/05)
Tandem: Allylic alcohols react with N-chlorosuccinimide (NCS) in a tandem 1,3-H shift/C-Cl bond formation leading to α-chloroketones and α-chloroaldehydes. The reactions proceed with complete selectivity to give single constitutional isomers of monochlorinated carbonyl compounds. The utility of the transformation is illustrated by the straightforward synthesis of 4,5-disubstituted 2-aminothiazoles from allylic alcohols. Copyright
Mild and efficient α-chlorination of carbonyl compounds using ammonium chloride and oxone (2KHSO5·KHSO4· K2SO4)
Swamy, Peraka,Kumar, MacHarla Arun,Reddy, Marri Mahender,Narender, Nama
supporting information; experimental part, p. 432 - 434 (2012/06/01)
A simple protocol for the α-monochlorination of ketones and 1,3-dicarbonyl compounds utilizing NH4Cl as a source of chlorine and Oxone as an oxidant in methanol without catalyst is presented. The reaction proceeds at ambient temperature in yields ranging from moderate to excellent.
OXIDATION OF OLEFINS USING CHROMIC ANHYDRIDE-CHLOROTRIMETHYLSILANE. A CONVENIENT SYNTHESIS OF α-CHLORO KETONES.
Lee, Jong Gun,Ha, Dong Soo
, p. 193 - 196 (2007/10/02)
Disubstituted internal olefins are oxidized selectively to α-chloro ketones in excellent yields from the reaction with chromic anhydride-chlorotrimethylsilane in carbon tetrachloride.
Metal-Catalyzed Organic Photoreactions. One-Step Synthesis of Chlorinated Ketones from Olefins by Photooxidation in the Presence of Iron(III) Chloride
Kohda, Akira,Ueda, Keiko,,Sato, Tadashi
, p. 509 - 515 (2007/10/02)
Under photooxidation in pyridine in the presence of FeCl3, mono- and disubstituted olefins gave α-chloro ketones, while tri- and tetrasubstituted olefins gave dichloro ketones with a C-C bond cleavage.The reaction was interpreted in terms of an electron-transfer mechanism occurring within the coordination sphere of the iron ion
