66252-09-3Relevant academic research and scientific papers
Additive-free radical cascade reaction of oxime esters: Synthesis of pyrroline-functionalized phenanthridines
Shao, Liming,Xue, Yijie,Xue, Dengqi,He, Qian,Ge, Qianwei,Li, Wei
, p. 12284 - 12293 (2020/11/10)
A variety of dihydropyrrole-functionalized phenanthridines were efficiently synthesized by the metal-free, radical cascade cyclization reaction of 2-isocyanobiphenyls with γ,δ- unsaturated oxime esters. The C-N/C-C/C-C bonds were formed via the oil bath method in a one-pot procedure with broad substrate applicability. The radical process was supported by kinetic isotope effect studies and radical inhibition studies.
