66262-01-9Relevant academic research and scientific papers
Efficient palladium-catalyzed nucleophilic addition of triorganoindium reagents to carbocyclic derivatives
Baker, Lucas,Minehan, Thomas
, p. 3957 - 3960 (2007/10/03)
Palladium (0)-catalyzed allylic substitution reactions employing triorganoindium reagents have been investigated. In situ generated vinyl- and arylindiums react with substituted and unsubstituted cyclohex-2-enyl esters in the presence of 1-3 mol % Pd2(dba)3 to produce vinyl- or arylcyclohexenes in moderate to excellent yields. The stereoselectivity of this process was also examined, and evidence is presented that the reaction proceeds with inversion of stereochemical configuration.
CYCLIC VINYL ETHER CARBANIONS-II PREPARATION AND APPLICATIONS TO THE SYNTHESIS OF CARBONYL COMPOUNDS
Boeckman, Robert K.,Bruza, Kenneth J.
, p. 3997 - 4006 (2007/10/02)
Conditions for metalation of a variety of cyclic vinyl ethers and reaction of the resulting carbanions with electrophiles are described.Effects of the vinyl ether structure on the relative rates of metalation are discussed.Applications of this methodology
