66262-70-2

Basic information

• Product Name: [2S-[2α,3β(1R*,2R*)]]-4,8-Anhydro-1,3,7-trideoxy-7-[[3-(2-hydroxy-1-Methylpropyl)oxiranyl]Methyl]-L-talo-2-octulose
• Synonyms: [2S-[2α,3β(1R*,2R*)]]-4,8-Anhydro-1,3,7-trideoxy-7-[[3-(2-hydroxy-1-Methylpropyl)oxiranyl]Methyl]-L-talo-2-octulose
• CAS NO: 66262-70-2
• Molecular Formula: C₁₅H₂₆O₆
• Molecular Weight: 302.36334
• Product Categories: Chiral Reagents, Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 66262-70-2.mol

Chemical Properties

• Boiling Point: 482.0±40.0 °C(Predicted)
• Appearance: /
• Density: 1.223±0.06 g/cm3(Predicted)
• Solubility: Chloroform, Dichloromethane, Methanol
• PKA: 13.70±0.70(Predicted)
• CAS DataBase Reference: [2S-[2α,3β(1R*,2R*)]]-4,8-Anhydro-1,3,7-trideoxy-7-[[3-(2-hydroxy-1-Methylpropyl)oxiranyl]Methyl]-L-talo-2-octulose(CAS DataBase Reference)
• NIST Chemistry Reference: [2S-[2α,3β(1R*,2R*)]]-4,8-Anhydro-1,3,7-trideoxy-7-[[3-(2-hydroxy-1-Methylpropyl)oxiranyl]Methyl]-L-talo-2-octulose(66262-70-2)
• EPA Substance Registry System: [2S-[2α,3β(1R*,2R*)]]-4,8-Anhydro-1,3,7-trideoxy-7-[[3-(2-hydroxy-1-Methylpropyl)oxiranyl]Methyl]-L-talo-2-octulose(66262-70-2)

Safety Data

• Hazardous Substances Data: 66262-70-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
[2S-[2α,3β(1R,2R)]]-4,8-Anhydro-1,3,7-trideoxy-7-[[3-(2-hydroxy-1-Methylpropyl)oxiranyl]Methyl]-L-talo-2-octulose is used as an intermediate in the preparation of Monic Acid A (M520500) and Monic Acid C. These natural products possess significant biological activities and potential therapeutic applications, making the intermediate a crucial component in the development of new drugs and pharmaceutical agents.

Upstream product

• 84109-57-9 (2S,4aS,7S,8R,8aR)-7-[(E)-(4R,5S)-5-(tert-Butyl-dimethyl-silanyloxy)-4-methyl-hex-2-enyl]-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-ol 
• 84109-57-9 (2S,4aS,7S,8R,8aR)-7-[(E)-5-(tert-Butyl-dimethyl-silanyloxy)-4-methyl-hex-2-enyl]-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-ol 
• 84109-59-1 (E)-(2S,3R)-6-((3aR,4S,7S,7aR)-4-Hydroxymethyl-2,2-dimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran-7-yl)-3-methyl-hex-4-en-2-ol 
• 84170-90-1 C₂₇H₂₈O₉S₂ 
• 84109-60-4 Toluene-4-sulfonic acid (3aR,4S,7S,7aR)-7-((E)-(4R,5S)-5-hydroxy-4-methyl-hex-2-enyl)-2,2-dimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran-4-ylmethyl ester 
• 84109-61-5 [(3aS,4S,7S,7aR)-7-((E)-(4R,5S)-5-Hydroxy-4-methyl-hex-2-enyl)-2,2-dimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran-4-yl]-acetonitrile 
• 84109-51-3 (1aR,3aS,6S,7aS,7bR)-6-Phenyl-hexahydro-1,3,5,7-tetraoxa-cyclopropa[a]naphthalene 
• 84109-62-6 1-[(2S,3R,4R,5S)-3,4-Dihydroxy-5-((E)-(4R,5S)-5-hydroxy-4-methyl-hex-2-enyl)-tetrahydro-pyran-2-yl]-propan-2-one 
• 87407-95-2 <(2S,3R,4R,5S)-3,4-bis<(trimethylsilyl)oxy>-5-<(2S,3S,4S,5S)-2,3-epoxy-5-<(trimethylsilyl)oxy>-4-methylhexyl>tetrahydropyran-2-yl>acetone 
• 84170-89-8 (2S,4aS,7R,8S,8aR)-2-Phenyl-hexahydro-pyrano[3,2-d][1,3]dioxine-7,8-diol 
• 84109-58-0 (2S,3R,4R,5S)-2-Hydroxymethyl-5-((E)-(4R,5S)-5-hydroxy-4-methyl-hex-2-enyl)-tetrahydro-pyran-3,4-diol 
• 84109-58-0 (2S,3R,4R,5S)-2-Hydroxymethyl-5-((E)-5-hydroxy-4-methyl-hex-2-enyl)-tetrahydro-pyran-3,4-diol 

Downstream Products

• 66262-53-1 ethyl monate A 
• 66262-53-1 ethyl isomonate 
• 66262-52-0 methyl isomonate 

Relevant articles and documents

The Chemistry of Pseudomonic Acid. Part 7. Stereochemical Control in the Preparation of C-2-substituted Monic Acid Esters via the Peterson Olefination

The preparation of 2-substituted monic acid esters (1, R H) by means of olefination reactions with the ketone (3b) and anions of the appropriate reagent (6) are described.Anions derived from 2-substituted phosphonoacetates generally did not react