66267-83-2Relevant academic research and scientific papers
Molecular Docking-Based Design and Development of a Highly Selective Probe Substrate for UDP-glucuronosyltransferase 1A10
Juvonen, Risto O.,Rauham?ki, Sanna,Kortet, Sami,Niinivehmas, Sanna,Troberg, Johanna,Petsalo, Aleksanteri,Huuskonen, Juhani,Raunio, Hannu,Finel, Moshe,Pentik?inen, Olli T.
, p. 923 - 933 (2018/03/13)
Intestinal and hepatic glucuronidation by the UDP-glucuronosyltransferases (UGTs) greatly affect the bioavailability of phenolic compounds. UGT1A10 catalyzes glucuronidation reactions in the intestine, but not in the liver. Here, our aim was to develop se
Synthesis and evaluation of two coumarin-type derivatization reagents for fluorescence detection of chiral amines and chiral carboxylic acids
Mertens, Matthias D.,Guetschow, Michael
, p. 957 - 964 (2014/01/06)
The synthesis of two fluorescent coumarin-type chiral derivatization agents (4 and 11) is reported. A chiral side chain was introduced at position 7 of the coumarin via Mitsunobu reaction. The two coumarins bear in this side chain either a free amino group or a carboxyl group, making them useful for further transformations. Conjugates of chiral prototype drugs with 4 or 11 were prepared by amide coupling of the analyte's carboxyl group to the reagent's amine group, or vice versa. The separation of seven diastereomeric conjugates through achiral high-performance liquid chromatography (HPLC) on a common C18 column is demonstrated. Chirality 25:957-964, 2013. 2013 Wiley Periodicals, Inc.
Highly soluble 7-oxy-3-(4-methoxyphenyl)coumarin bearing zinc phthalocyanines: Synthesis and investigation of photophysical and photochemical properties
Pikin, Mehmet,Durmu, Mahmut,Bulut, Mustafa
body text, p. 37 - 49 (2012/02/14)
The synthesis of 7-oxy-3-(4-methoxyphenyl)coumarin-substituted peripherally and non-peripherally tetrakis- and peripherally octakis-tetrachloro zinc(II) phthalocyanine complexes are described for the first time in this study. The new compounds have been c
Modified coumarins. 29. Synthesis of structural analogs of natural 6-arylfuro[3,2-g]chromen-7-ones
Garazd,Garazd,Ogorodniichuk,Khilya
experimental part, p. 158 - 163 (2009/12/06)
3-Substituted 6-arylfuro[3,2-g]chromen-7-ones, structural analogs of natural furocoumarins, were synthesized by linear annelation of a furan fragment to a 3-arylcoumarin system.
Synthesis and binding affinity of 3-aryl-7-hydroxycoumarins to human α and β estrogen receptors
Kirkiacharian,Lormier,Resche-Rigon,Bouchoux,Cérède
, p. 51 - 56 (2007/10/03)
The synthesis of a set of substituted 3-aryl-7-hydroxycoumarins was performed. The study of the relations between their structure and their relative binding affinity (RBA) to human α and β estrogen receptors was achieved.
