6627-22-1

Basic information

• Product Name: methyl 6-chloropyrimidine-4-carboxylate
• Synonyms: methyl 6-chloropyrimidine-4-carboxylate;4-PyriMidinecarboxylic acid, 6-chloro-, Methyl ester;Methyl 6-chloro-4-pyrimidinecarboxylate;NSC 58346
• CAS NO: 6627-22-1
• Molecular Formula: C6H5ClN2O2
• Molecular Weight: 172.57
• Mol File: 6627-22-1.mol

Chemical Properties

• Boiling Point: 271℃
• Flash Point: 118℃
• Appearance: /
• Density: 1.372
• Vapor Pressure: 0.00652mmHg at 25°C
• Refractive Index: 1.534
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -2.89±0.17(Predicted)
• CAS DataBase Reference: methyl 6-chloropyrimidine-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 6-chloropyrimidine-4-carboxylate(6627-22-1)
• EPA Substance Registry System: methyl 6-chloropyrimidine-4-carboxylate(6627-22-1)

Safety Data

• Hazardous Substances Data: 6627-22-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Methyl 6-chloropyrimidine-4-carboxylate is used as a key intermediate in the synthesis of pharmaceuticals for its ability to be incorporated into the molecular structures of various drugs. Its unique chemical properties allow for the development of new therapeutic agents with potential applications in treating a range of diseases and conditions.
Used in Agrochemical Industry:
In the agrochemical industry, methyl 6-chloropyrimidine-4-carboxylate is utilized as a building block for the preparation of agrochemicals. Its incorporation into the molecular structures of these compounds can enhance their effectiveness in protecting crops from pests and diseases, thereby contributing to increased agricultural productivity.
Used in Organic Synthesis:
Methyl 6-chloropyrimidine-4-carboxylate serves as a versatile building block in organic synthesis, allowing for the creation of a variety of biologically active compounds. Its unique structural features make it an essential component in the development of new chemical entities with potential applications in various fields, including medicine, agriculture, and materials science.

InChI:InChI=1/C6H5ClN2O2/c1-11-6(10)4-2-5(7)9-3-8-4/h2-3H,1H3

Downstream Products

• 1590397-67-3 2-(4-fluoro-N-isopropylphenylsulfonamido)-N-((6-(4-(trifluoromethyl)cyclohex-1-enyl)pyrimidin-4-yl)methyl)acetamide 
• 1590398-38-1 [6-[4-(trifluoromethyl)cyclohex-1-en-1-yl]pyrimidin-4-yl]methanamine 
• 1590398-37-0 2-([6-[4-(trifluoromethyl)cyclohex-1-en-1-yl]pyrimidin-4-yl]methyl)2,3-dihydro-1H-isoindole-1,3-dione 
• 1590398-36-9 [6-[4-(trifluoromethyl)cyclohex-1-en-1-yl]pyrimidin-4-yl]methanol 
• 1590398-35-8 methyl 6-(4-(trifluoromethyl)cyclohex-1-enyl)pyrimidine-4-carboxylate 
• 1426320-85-5 ethyl 6-{3-chloro-4-[cyclopropyl(hydroxy)methyl]phenyl}pyrimidine-4-carboxylate 
• 1224465-32-0 methyl 6-((5S,9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]nonan-7-yl)pyrimidine-4-carboxylate 
• 1208980-42-0 methyl 6-(4-hydroxyphenylamino)pyrimidine-4-carboxylate 
• 1114592-39-0 methyl 6-(cyclohexylamino)pyrimidine-4-carboxylate 
• 1207723-92-9 6-(2,4-difluorophenyl)pyrimidine-4-carboxylic acid methyl ester 
• 1426320-17-3 6-{3-chloro-4-[(dimethylamino)methyl]phenyl}pyrimidine-4-carboxylic acid 
• 1025351-41-0 (6-chloropyrimidin-4-yl)methanol