66280-26-0 Usage
Uses
Used in Neurological Disorders Treatment:
Pregomisin is used as a therapeutic agent for managing neuropathic pain associated with conditions such as diabetic neuropathy, postherpetic neuralgia, and other similar neurological disorders. The combination of pregabalin and mecobalamin in Pregomisin works synergistically to alleviate symptoms and improve the quality of life for patients suffering from these conditions.
Used in Vitamin B12 Deficiency Treatment:
Pregomisin is used as a supplement for treating vitamin B12 deficiency, particularly in cases of pernicious anemia and related neuropathies. Mecobalamin, the vitamin B12 component, plays a crucial role in the normal functioning of the brain and nervous system, and its inclusion in Pregomisin helps in correcting any deficiencies that may contribute to neurological symptoms.
Check Digit Verification of cas no
The CAS Registry Mumber 66280-26-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,2,8 and 0 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 66280-26:
(7*6)+(6*6)+(5*2)+(4*8)+(3*0)+(2*2)+(1*6)=130
130 % 10 = 0
So 66280-26-0 is a valid CAS Registry Number.
InChI:InChI=1/C22H30O6/c1-13(7-15-9-17(23)21(27-5)19(11-15)25-3)14(2)8-16-10-18(24)22(28-6)20(12-16)26-4/h9-14,23-24H,7-8H2,1-6H3/t13-,14+
66280-26-0Relevant academic research and scientific papers
Synthesis of Lignans Based on a Borate-mediated One-pot Sequential Suzuki-Miyaura Coupling of Cyclic Boranes
Sato, Ko,Tanaka, Hiroshi
supporting information, p. 9422 - 9428 (2021/05/26)
Lignans are a group of polyphenolic phytochemicals that possess a large spectrum of chemical structures and biological activities. Here the syntheses of lignans – anwulignan, burseran, dehydroxycubebin, ruburisandrin B, and sesamin – are achieved based on a borate-mediated one-pot sequential Suzuki-Miyaura coupling of cis- and trans-fused bicyclic boranes, which were prepared by diastereoselective cyclic hydroboration of exo-cyclic diene with cyclopentyl- and thexylboranes, respectively. A one-pot sequential Suzuki-Miyaura coupling of each cyclic borate with various aryl bromides initiated by activation of the cyclic borane with the carbon nucleophile provided 2,3-dibenzylbutane derivatives with different aromatic substituents. Finally, the syntheses of naturally occurring lignans were accomplished in several steps from the products of Suzuki-Miyaura coupling.
