66286-25-7Relevant academic research and scientific papers
Iron-Catalyzed ortho C?H Arylation and Methylation of Pivalophenone N?H Imines
Xu, Wengang,Yoshikai, Naohiko
, p. 3049 - 3053 (2019/03/13)
Iron-catalyzed ortho C?H arylation and methylation reactions of pivalophenone N?H imines are reported. The pivaloyl N?H imine proved an excellent directing group for the arylation with diarylzinc reagents in the presence of an iron-diphosphine catalyst an
P -Selective (sp2)-C-H functionalization for an acylation/alkylation reaction using organic photoredox catalysis
Pandey, Ganesh,Tiwari, Sandip Kumar,Singh, Bhawana,Vanka, Kumar,Jain, Shailja
, p. 12337 - 12340 (2017/11/20)
p-Selective (sp2)-C-H functionalization of electron rich arenes has been achieved for acylation and alkylation reactions, respectively, with acyl/alkylselenides by organic photoredox catalysis involving an interesting mechanistic pathway.
Friedel-Crafts acylation reaction using carboxylic acids as acylating agents
Kawamura, Masato,Cui, Dong-Mei,Shimada, Shigeru
, p. 9201 - 9209 (2007/10/03)
Dehydrative Friedel-Crafts acylation reaction of aromatic compounds with carboxylic acids as acylating agents was investigated in the presence of Lewis acid- or Br?nsted acid-catalyst. Various metal triflates and bis(trifluoromethanesulfonyl)amides showed catalytic activity at high temperature, among which Eu(NTf2)3 proved to be the most effective and efficiently catalyzed the acylation reaction of alkyl- and alkoxybenzenes with aliphatic and aromatic carboxylic acids at 250 °C. Bi(NTf2)3 was more effective than Eu(NTf2)3 at lower temperature, but proved to be hydrolyzed in the presence of a small amount of water to give HNTf2 and [Bi6O4(OH)4(H2O)6](NTf2)6. The structure of the latter compound was confirmed by a single crystal X-ray analysis. Among five Br?nsted acids, HOTf, HNTf2, HCTf3, TsOH, and Nafion SAC-13, HNTf2 has proved to be the most efficient catalyst and more effective than Eu(NTf2)3 for the acylation of p-xylene with heptanoic acid at 220 °C or lower temperature. HNTf2 catalyzed the acylation of anisole with carboxylic acids in high yields in refluxing toluene with azeotropic removal of water.
Lewis acid-catalyzed Friedel-Crafts acylation reaction using carboxylic acids as acylating agents
Kawamura, Masato,Cui, Dong-Mei,Hayashi, Teruyuki,Shimada, Shigeru
, p. 7715 - 7717 (2007/10/03)
Rare-earth metal Lewis acids, in particular Eu(NTf2) 3, were found to be efficient catalysts for Friedel-Crafts acylation reaction using aliphatic as well as aromatic carboxylic acids as acylating agents at high temperature.
