663155-50-8

Basic information

• Product Name: 1H-Inden-1-one, 3a,4,5,6,7,7a-hexahydro-2-methyl-, (3aR,7aR)-rel- (9CI)
• Synonyms: 1H-Inden-1-one, 3a,4,5,6,7,7a-hexahydro-2-methyl-, (3aR,7aR)-rel- (9CI)
• CAS NO: 663155-50-8
• Molecular Formula: C10H14O
• Molecular Weight: 150.21756
• Product Categories: CYCLOPENTANE;ALCOHOL
• Mol File: 663155-50-8.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-Inden-1-one, 3a,4,5,6,7,7a-hexahydro-2-methyl-, (3aR,7aR)-rel- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Inden-1-one, 3a,4,5,6,7,7a-hexahydro-2-methyl-, (3aR,7aR)-rel- (9CI)(663155-50-8)
• EPA Substance Registry System: 1H-Inden-1-one, 3a,4,5,6,7,7a-hexahydro-2-methyl-, (3aR,7aR)-rel- (9CI)(663155-50-8)

Safety Data

• Hazardous Substances Data: 663155-50-8(Hazardous Substances Data)

Upstream product

• 663155-48-4 (Z)-3-(cyclohex-1-en-1-yl)-2-(trimethylsilylmethyl)prop-2-enal 
• 101-43-9 cyclohexyl methacrylate 

Relevant articles and documents

Synthesis of spiro[4.5]decane and bicyclo[4.3.0]nonane ring systems by self-cyclization of (Z)- and (E)-2-(trimethylsilylmethyl)pentadienal derivative

The two title carbon frameworks were synthesized utilizing a new type of iron-induced cyclization reaction of 2-(trimethylsilylmethyl)pentadienal. 2-Methylspiro[4.5]dec-2-en-1-one was obtained from (Z)- and (E)-4- cyclohexylidene-2-(trimethylsilylmethyl)but-2-enal. It was found that the (Z)-substrate isomerized to (E)-intermediate followed by cyclization to afford the initial product, 2-methylenespiro[4.5]dec-3-en-1-ol, which was isomerized to the above product. The cyclization of 4-(4-alkyl)cyclohexylidene-2- (trimethylsilylmethyl)but-2-enal proceeded stereoselectively. While, (E)-3-(cyclohex-1-en-1-yl)-2-(trimethylsilylmethyl)prop-2-en-1-al cyclized immediately affording 8-methylenebicyclo[4.3.0]non-9-en-7-ol. The corresponding (Z)-isomer gave several cyclization products as a complex mixture.