6632-09-3

Basic information

• Product Name: 7-(PIPERIDIN-1-YLMETHYL)QUINOLIN-8-OL
• Synonyms: OTAVA-BB BB7010150234;7-(PIPERIDIN-1-YLMETHYL)QUINOLIN-8-OL;AKOS BBS-00001111;AURORA 23227;7-(1-piperidinylmethyl)-8-hydroxyquinoline
• CAS NO: 6632-09-3
• Molecular Formula: C₁₅H₁₈N₂O
• Molecular Weight: 242.32
• Mol File: 6632-09-3.mol
• Article Data: 3

Chemical Properties

• Melting Point: 194 °C
• Boiling Point: 402.4°Cat760mmHg
• Flash Point: 197.2°C
• Appearance: /
• Density: 1.202g/cm³
• Vapor Pressure: 4.73E-07mmHg at 25°C
• Refractive Index: 1.65
• PKA: 3.81±0.50(Predicted)
• CAS DataBase Reference: 7-(PIPERIDIN-1-YLMETHYL)QUINOLIN-8-OL(CAS DataBase Reference)
• NIST Chemistry Reference: 7-(PIPERIDIN-1-YLMETHYL)QUINOLIN-8-OL(6632-09-3)
• EPA Substance Registry System: 7-(PIPERIDIN-1-YLMETHYL)QUINOLIN-8-OL(6632-09-3)

Safety Data

• Hazardous Substances Data: 6632-09-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C15H18N2O/c18-15-13(11-17-9-2-1-3-10-17)7-6-12-5-4-8-16-14(12)15/h4-8,18H,1-3,9-11H2

Upstream product

• 110-89-4 piperidine 
• 148-24-3 8-quinolinol 
• 50-00-0 formaldehyd 

Downstream Products

• 1412494-53-1 (4-bromophenyl)(furo[3,2-h]quinolin-2-yl)methanone 
• 1187741-86-1 triphenyl(3,4-dihydro-2,2,2-triphenyl-2H-1,2-oxaphosphino[5,6-h]quinolin-3-ylidene)phosphine 

Relevant articles and documents

Biocidal activity of some Mannich base cationic derivatives

A novel series of cationic surfactants was prepared based on Mannich base (produced from the condensation of piperidine and/or morpholine as secondary amine and paraformaldehyde in the presence of 8-hydroxyquinoline). The chemical structures of the synthesized cationic surfactants were confirmed using elemental analyses, FTIR spectroscopy and 1H NMR. Surface activities of the prepared surfactants were measured including: surface tension (γ), critical micelle concentration (CMC), effectiveness (πCMC), efficiency (Pc20), maximum surface excess (Γmax), minimum surface area (Amin), interfacial tension (γ IT), emulsification power and foaming power at 25°C. The structural influences on their surface activities and adsorption free energy were discussed. The synthesized cationic surfactants were evaluated for their biocidal activity towards Gram +ve bacteria (Staph. Cocu., Bacillus), Gram -ve bacteria (Salmonella, E. coli), fungi (A. terrus., A. flav.) and yeast (Candida) at 1.0, 2.5 and 5.0 mg/mL, respectively. The target compounds showed good inhibition towards Gram +ve bacteria, Gram -ve bacteria and yeast. Meanwhile, excellent fungicidal results were obtained against the various types of fungi under investigation.

Study on Relationship Between Fluorescence Properties and Structure of Substituted 8-Hydroxyquinoline Zinc Complexes

Organic light-emitting diodes (OLEDs) produced from 8-hydroxyquinoline metal complexes play a vital role in modern electroluminescent devices. In this manuscript, a series of 8-hydroxyquinoline derivatives were synthesized by different methods and their corresponding zinc metal complexes were prepared. The UV and fluorescence properties of the complexes were measured aiming to understand the effect of substituents at the quinoline ring on the fluorescence properties of the complexes. When the C-5 of 8-hydroxyquinoline was replaced by halogen group, the fluorescence emission wavelengths had been red-shifted, at the same time, blue-shifted of fluorescence emission wavelength was observed when the C-5 position of 8-hydroxyquinoline was substituted by electron-withdrawing group. When the C-4 position of 8-hydroxyquinolie was substituted by methyl or the C-5 position was substituted by sulfonic acid group, the corresponding zinc complexes had higher fluorescence intensity than 8-hydroxyquinolie zinc.