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3'-AZIDO-2'-3'-DIDEOXYGUANOSINE, commonly known as AZT or zidovudine, is an antiretroviral medication that plays a crucial role in the treatment of HIV/AIDS. It functions by inhibiting the reverse transcriptase enzyme, which is essential for the replication of the virus. As a nucleoside analog, AZT mimics the structure of natural nucleosides in DNA, integrating itself into the viral DNA and disrupting the replication process, thus preventing the virus from multiplying. Since its introduction in the 1980s, AZT has been instrumental in improving the prognosis for individuals living with HIV/AIDS.

66323-46-4

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66323-46-4 Usage

Uses

Used in Pharmaceutical Industry:
3'-AZIDO-2'-3'-DIDEOXYGUANOSINE is used as an antiretroviral agent for the treatment of HIV/AIDS. It is employed to inhibit the reverse transcriptase enzyme, which is necessary for the virus to replicate, thereby slowing the progression of the disease and improving the prognosis for individuals living with the condition.
Used in Combination Therapies:
AZT is often used in combination with other antiretroviral medications to create highly active antiretroviral therapy (HAART). This approach helps to reduce the viral load in the body and minimize the risk of drug resistance, leading to more effective treatment outcomes for HIV/AIDS patients.
Used in Research and Development:
3'-AZIDO-2'-3'-DIDEOXYGUANOSINE serves as a valuable compound in the ongoing research and development of new antiretroviral medications and therapies. Its mechanism of action and role in disrupting the replication process of the virus provide insights for the design of novel drugs and treatment strategies to combat HIV/AIDS.

Check Digit Verification of cas no

The CAS Registry Mumber 66323-46-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,3,2 and 3 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 66323-46:
(7*6)+(6*6)+(5*3)+(4*2)+(3*3)+(2*4)+(1*6)=124
124 % 10 = 4
So 66323-46-4 is a valid CAS Registry Number.

66323-46-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 3'-AZIDO-2'-3'-DIDEOXYGUANOSINE

1.2 Other means of identification

Product number -
Other names 3'-AZIDO-2'-DEOXY-D-GUANOSINE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:66323-46-4 SDS

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