66328-69-6

Usage

Uses

Used in Pharmaceutical Industry:
4-AMINO-5-NITROFURAZANE is used as an intermediate in the synthesis of various pharmaceuticals for its antimicrobial and antitumor properties, contributing to the development of treatments for infectious diseases and cancer.
Used in Organic Compounds Synthesis:
In the field of organic chemistry, 4-AMINO-5-NITROFURAZANE is utilized as a starting material for synthesizing a range of nitrogen-containing organic compounds, expanding the scope of chemical research and applications.
Used in Explosive Materials Production:
4-AMINO-5-NITROFURAZANE is employed in the production of explosive materials due to its inherent explosive properties, making it a component in the development of pyrotechnics and other related applications.

InChI:InChI=1/C2H2N4O3/c3-1-2(6(7)8)5-9-4-1/h(H2,3,4)

Upstream product

• 146859-32-7 1,3-dinitro-1,3-bis(4-nitrofurazan-3-yl)-1,3-diazapropane 
• 17220-38-1 3,4-diaminofurazan 
• 155438-30-5 3,4-Dinitrofurazan 
• 292836-18-1 4-amino-3-(4-hydroxymethyl-1,2,3-triazol-1-yl)furazan 
• 292836-19-2 (1-(4-amino-1,2,5-oxadiazol-3-yl)-1H-1,2,3-triazol-5-yl)methanol 
• 292836-31-8 4-amino-3-[4,5-bis(hydroxymethyl)-1,2,3-triazol-1-yl]furazan 
• 152845-81-3 4,4'-di(3-nitrofurazanyl) ether 

Downstream Products

• 78350-48-8 3-amino-4-methoxyfurazan 
• 155438-10-1 dinitroazofurazane 
• 205323-38-2 4,4'-dinitroazofurazan 
• 129282-34-4 4-Phenoxy-furazan-3-ylamine 
• 155438-10-1 4,4'-dinitroazofurazan 
• 1415932-13-6 4-nitro-3-(1-nitrocyclohex-1-yl-ONN-azoxy)furazan 
• 761448-37-7 3-amino-4-(2-hydroxybutoxy-3)-furazan 
• 17557-81-2 3,4-dicyano-1,2,5-oxadiazole 2-oxide 
• 162111-06-0 3-azido-4-nitrofurazan 
• 292856-68-9 3-amino-4-(4-methoxyphenoxy)-furazan 

Relevant academic research and scientific papers

Synthesis of nitro, nitroso, azo, and azido derivatives of (4-R 1-5-R2-1,2,3-triazol-1-yl)-1,2,5-oxadiazoles by oxidation and diazotization of the corresponding amines

Nitro-, nitroso-, and azo-1,2,5-oxadiazoles with 4-R1-5-R 2-1,2,3-triazol-1-yl substituents were synthesized by oxidation of amino-(1,2,3-triazol-1-yl)-1,2,5-oxadiazoles (aminotriazolylfurazans). Azido-1,2,5-oxadiazole was prepared b

Synthesis, Characterization and Properties of Ureido-Furazan Derivatives

The reaction of a variety of amino-furazans with chlorosulfonyl isocyanate was carried out to synthesize ureido-furazans. The nitration to nitro-ureido-furazan was successful in the case of 3-nitro-4-nitroureido-furazan and 3,4-dinitroureido-furazan. Furthermore, furazan derivatives linked to a second amino-oxadiazole were synthesized. All compounds were intensively characterized by X-ray diffraction measurements, NMR spectroscopy, vibrational spectroscopy (IR, Raman), BAM sensitivity tests and differential thermal analysis. The energetic properties were calculated using Explo5 6.03.

Synthesis of secondary and tertiary aminofurazans

Reactions of nitrofurazans with primary and secondary amines were studied. Conditions were found which allow the efficient replacement of the nitro group with these nucleophiles. Transformations of the amidoxime fragment, which is bound to the furazan ring and contains an amino substituent, enable one to substantially expand the spectrum of polyfunctional derivatives. The structures of the amines synthesized were studied by X-ray diffraction analysis.

Nucleophilic substitution in the furazan series. Reactions of nitrofurazans with ammonia

The reactions of 3-nitro-4-R-furazans with ammonia were studied. The effect of the substituent R on the specific features of the nucleophilic substitution reaction observed was considered. The nitro group attached to the furazan ring can act as both the l

Synthesis and Structure of Dinitroazofurazan

The synthesis of dinitroazofurazan (3) was achieved from readily available diaminofurazan (6) in two steps and 20% overall yield. The structure of the energetic material 3 was unequivocally confirmed by X-ray crystallography and found to have a crystal density of 1.742 g/cm3.

New method for the synthesis of 1,2,3-triazole 1-oxides

A general method is proposed for the synthesis of 1,2,3-triazole 1-oxides using 3,4-dinitro- or 4-amino-3-nitrofuroxanes. 1996 Plenum Publishing Corporation.

OXIDATION OF 3,4-DIAMINOFURAZAN BY SOME PEROXIDE REAGENTS

3-Amino-4-nitrofurazan, 4,4'-diamino-3,3'-azoxyfurazan, and 4,4'-diamino-3,3'-azofurazan were obtained by the oxidation of 3,4-diaminofurazan with neutral Caro's acid, ammonium persulfate, hydrogen peroxide, and their mixture.The composition of the oxidation products depends on the ratio of the reagents and on the acidity of the medium.