6634-87-3

Basic information

• Product Name: BENZOTHIAZOL-2-YL-(4-ETHOXY-PHENYL)-AMINE
• Synonyms: 2-benzothiazolamine, N-(4-ethoxyphenyl)-; Benzothiazol-2-yl-(4-ethoxy-phenyl)-amine; N-(4-Ethoxyphenyl)-1,3-benzothiazol-2-amine
• CAS NO: 6634-87-3
• Molecular Formula: C₁₅H₁₄N₂OS
• Molecular Weight: 270.35
• Mol File: 6634-87-3.mol
• Article Data: 3

Chemical Properties

• Melting Point: 165-167 °C
• Boiling Point: 422.2°C at 760 mmHg
• Flash Point: 209.2°C
• Appearance: /
• Density: 1.27g/cm³
• Vapor Pressure: 2.45E-07mmHg at 25°C
• Refractive Index: 1.689
• PKA: 3.00±0.10(Predicted)
• CAS DataBase Reference: BENZOTHIAZOL-2-YL-(4-ETHOXY-PHENYL)-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: BENZOTHIAZOL-2-YL-(4-ETHOXY-PHENYL)-AMINE(6634-87-3)
• EPA Substance Registry System: BENZOTHIAZOL-2-YL-(4-ETHOXY-PHENYL)-AMINE(6634-87-3)

Safety Data

• Hazardous Substances Data: 6634-87-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C15H14N2OS/c1-2-18-12-9-7-11(8-10-12)16-15-17-13-5-3-4-6-14(13)19-15/h3-10H,2H2,1H3,(H,16,17)

Upstream product

• 615-20-3 2-chlorobenzo[d][1,3]thiazole 
• 156-43-4 4-Ethoxyaniline 
• 615-43-0 2-iodophenylamine 
• 3460-49-9 1-ethoxy-4-isothiocyanatobenzene 
• 103-72-0 phenyl isothiocyanate 
• 136-95-8 2-amino-benzthiazole 
• 1756-43-0 N-(4-ethoxyphenyl)-N'-phenylthiourea 

Relevant articles and documents

Copper/N,N,N',N'-tetramethylethylenediamine-catalyzed synthesis of N-substituted benzoheterocycles via C-S cross-coupling at ambient temperature in water

Copper/N,N,N',N'-tetramethylethylenediamine (Cu/TMEDA)-catalyzed ambient temperature tandem reactions of isothiocyanates with 2-iodophenols or 2-iodoanilines in water without the protection of an inert atmosphere are described, which provide a simple, rapid, environmental method for the synthesis of a variety of 2-iminobenzo-1, 3- oxathioles and 2-aminobenzothiazoles in good yields. More important, the present reaction process needs only low amounts of copper catalyst (1mol%) and can yield the products on a gram scale.

Benzothiazolyl derivatives

The present invention relates to compounds of formula (I) wherein R1, R2, R3°R3a and R3b are as provided in the description, and pharmaceutically acceptable salts thereof, for use in the treatment and