66400-26-8

Basic information

• Product Name: 1,3-dicyclohexyl-6-(methylamino)pyrimidine-2,4(1H,3H)-dione
• CAS NO: 66400-26-8
• Molecular Formula: C₁₇H₁₅N₃O₂
• Molecular Weight: 305.4152
• Mol File: 66400-26-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 436.9°C at 760 mmHg
• Flash Point: 218°C
• Density: 1.16g/cm³
• Vapor Pressure: 7.81E-08mmHg at 25°C
• Refractive Index: 1.571
• CAS DataBase Reference: 1,3-dicyclohexyl-6-(methylamino)pyrimidine-2,4(1H,3H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-dicyclohexyl-6-(methylamino)pyrimidine-2,4(1H,3H)-dione(66400-26-8)
• EPA Substance Registry System: 1,3-dicyclohexyl-6-(methylamino)pyrimidine-2,4(1H,3H)-dione(66400-26-8)

Safety Data

• Hazardous Substances Data: 66400-26-8(Hazardous Substances Data)

Downstream Products

• 871699-90-0 ethyl (6-methylamino-2,4-dioxo-1,3-diphenyl-1,2,3,4-tetrahydro-pyrimidine-5-thiocarbonyl)-carbamate 
• 177082-81-4 9-Chloro-5-methyl-2,4-diphenyl-4H,5H-2,4,5,12-tetraaza-benzo[a]anthracene-1,3,6-trione 
• 177082-79-0 5,9-Dimethyl-2,4-diphenyl-4H,5H-2,4,5,12-tetraaza-benzo[a]anthracene-1,3,6-trione 
• 177082-54-1 8-methyl-1,3-diphenyl-5-(4-toluenesulfonyloxy)-pyrido<2,3-d>pyrimidine-2,4,7(1H,3H,8H)-trione 
• 177082-62-1 8-Methyl-1,3-diphenyl-5-phenylamino-1H,8H-pyrido[2,3-d]pyrimidine-2,4,7-trione 
• 177082-44-9 5-hydroxy-8-methyl-1,3-diphenyl-pyrido<2,3-d>pyrimidine-2,4,7-trione 

Relevant articles and documents

5-AMINO-2,4,7-TRIOXO-3,4,7,8-TETRAHYDRO-2H-PYRIDO’2,3-D! PYRIMIDINE DERIVATIVES AND RELATED COMPOUNDS FOR THE TREATMENT OF CANCER

The present invention relates to a pyrimidine compound represented by the following formula [I] wherein each symbol is as defined in the specification, a pharmaceutically acceptable salt thereof, and a pharmaceutical agent for the prophylaxis or treatment of a disease caused by undesirable cell proliferation, particularly an antitumor agent, which contains such compound. The compound of the present invention has superior undesirable cell proliferation suppressing action, particularly, an antitumor action, and is useful as an antitumor agent for the prophylaxis or treatment of cancer, antirheumatoid agent and the like. In addition, by the combined use with other antitumor agent such as alkylating agent, metabolism antagonist and the like, it can be a more effective antitumor agent.