66407-74-7Relevant academic research and scientific papers
Copper-catalyzed P-H insertion reactions of sulfoxonium ylides
Jiang, Jun,Liang, Cuijian,Zhang, Xinzhi,Zhang, Yangyang
, p. 5767 - 5771 (2021)
A copper-catalyzed P-H insertion reaction between sulfoxonium ylides and H-phosphorus oxides has been demonstrated, furnishing α-phosphonyl carboxylate derivatives in 41-93% yields. This methodology utilizing bench-stable and thermodynamically stable sulfoxonium ylides as carbene precursors in the presence of the inexpensive and readily available copper catalyst shows advantages such as mild reaction conditions, good functional group compatibility, and easy scale-up, which make this protocol attractive for large-scale chemical processing and processing at the industrial scale.
Reductive coupling reactions: A new strategy for C(sp3)-P bond formation
Chen, Zi-Sheng,Zhou, Zhao-Zhao,Hua, Hui-Liang,Duan, Xin-Hua,Luo, Jian-Yi,Wang, Jia,Zhou, Ping-Xin,Liang, Yong-Min
, p. 1065 - 1068 (2013/02/25)
The C(sp3)-P bond forming reaction utilizing N-tosylhydrazones as readily available alkylating reagents was developed, which provides a new opportunity for preparing phosphine oxide derivatives with moderate to good yields. This reductive coupling reaction is proposed to proceed through an insertion of copper carbene into P-H bond of H-phosphorus oxides. The salient features of the reaction are operational simplicity and functional-group tolerance.
