6641-75-4Relevant academic research and scientific papers
A novel Pd-catalyzed N-dealkylative carbonylation of tertiary amines for the preparation of amides
Fang, Tao,Gao, Xu-Hong,Tang, Ri-Yuan,Zhang, Xing-Guo,Deng, Chen-Liang
supporting information, p. 14775 - 14777 (2014/12/11)
A novel and convenient protocol for the formation of amides via palladium-catalyzed N-dealkylative carbonylation of alkyl tertiary amines has been developed. In the presence of PdCl2(PhCN)2, CuO, PhCN and CO, a range of substituents on both aryl iodides and alkyl tertiary amines were compatible with the reaction to afford a series of N,N-disubstituted amides in moderate to excellent yields. This journal is
