66411-18-5

Basic information

• Product Name: 6,7-Dibromo-8-nitro-2,3-dihydrobenzo[1,4]dioxine-5-carboxylic acid
• Synonyms: 6,7-Dibromo-8-nitro-2,3-dihydrobenzo[1,4]dioxine-5-carboxylic acid;6,7-Dibromo-8-nitro-2,3-dihydrobenzo-[b][1,4]dioxine-5-carboxylic acid
• CAS NO: 66411-18-5
• Molecular Formula: C9H5Br2NO6
• Molecular Weight: 382.96
• Mol File: 66411-18-5.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 6,7-Dibromo-8-nitro-2,3-dihydrobenzo[1,4]dioxine-5-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 6,7-Dibromo-8-nitro-2,3-dihydrobenzo[1,4]dioxine-5-carboxylic acid(66411-18-5)
• EPA Substance Registry System: 6,7-Dibromo-8-nitro-2,3-dihydrobenzo[1,4]dioxine-5-carboxylic acid(66411-18-5)

Safety Data

• Hazardous Substances Data: 66411-18-5(Hazardous Substances Data)

Upstream product

• 66411-17-4 6,7-dibromo-2,3-dihydrobenzo[b][1,4]dioxine-5-carboxylic acid 
• 4442-53-9 2,3-dihydro-1,4-benzodioxine-5-carboxylic acid 

Downstream Products

• 66411-22-1 8-amino-2,3-dihydrobenzo[b][1,4]dioxine-5-carboxylic acid 
• 158504-37-1 methyl 8-amino-2,3-dihydrobenzo[b][1,4]dioxine-5-carboxylate 
• 148703-26-8 8-amino-7-chloro-2,3-dihydro-benzo[1,4]dioxine-5-carboxylic acid 

Relevant articles and documents

MDM2 DEGRADERS AND USES THEREOF

The present invention relates to compounds and methods useful for the modulation of mouse double minute 2 homolog ("MDM2") protein via ubiquitination and/or degradation by compounds according to the present invention.

2-PHENYLAMINOPYRIMIDINE DERIVATIVES AS KINASE LRRK2 MODULATORS FOR THE TREATMENT OF PARKINSON'S DISEASE

Specific Compounds of formula (I): or pharmaceutically acceptable salts thereof, wherein m, X, R, R2, R3, R, R6 and R7 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of diseases associated with LRRK2 receptor, such as Parkinson's disease.