66416-73-7

Usage

Uses

Used in Organic Synthesis:
4-Amino-3-iodophenol is used as a reagent in organic synthesis for the preparation of various chemical compounds. Its unique structure with an amino and iodine atom allows for versatile reactions and the formation of a wide range of products.
Used in Pharmaceutical Industry:
4-Amino-3-iodophenol is used as a building block in the pharmaceutical industry for the preparation of various drugs. Its potential biological activities, including antioxidant and anti-inflammatory properties, make it a valuable component in the development of new medications.
Used in Dye Industry:
4-Amino-3-iodophenol is used as a building block in the dye industry for the preparation of various dyes. Its unique chemical structure contributes to the color and properties of the resulting dyes.
Used in Research and Development:
4-Amino-3-iodophenol is used in research and development for studying its potential biological activities and exploring its applications in various fields. Its antioxidant and anti-inflammatory properties make it a promising candidate for further investigation and development.

Upstream product

• 50590-07-3 3-iodo-4-nitrophenol 
• 41319-82-8 2-iodophenyl hydroxylamine 
• 305-80-6 4-diazobenzenesulfonic acid 
• 626-02-8 3-Iodophenol 

Downstream Products

• 3958-83-6 2-iodocyclohexa-2,5-diene-1,4-dione 
• 66417-31-0 2-Amino-5-hydroxystilben 
• 626-02-8 3-Iodophenol 
• 388564-62-3 (4-hydroxy-2-iodo-phenyl)-carbamic acid benzyl ester 
• 460721-26-0 acetic acid 4-amino-3-iodo-phenyl ester 
• 191348-14-8 2-iodo-4-methoxylaniline 
• 496881-71-1 2-iodohydroquinone diacetate 
• 22944-03-2 Siccayne 
• 22944-04-3 siccayne diacetate 
• 157496-75-8 tert-butyl (2-iodo-4-methoxyphenyl)carbamate 

Relevant academic research and scientific papers

Total synthesis of ibogaine, epiibogaine and their analogues

Efficient total synthesis of ibogaine, epiibogaine and their analogues has been described. An intramolecular reductive-Heck type cyclization was used for the construction of seven-membered indoloazepine ring to access iboga-skeleton. Larock's heteroannula

Synthesis and biological activity of 5-aza-ellipticine derivatives

Novel 5-aza-ellipticine derivatives were synthesized and tested as antitumor agents. The new compounds were prepared more readily than the analogous ellipticine derivatives, which are known to be potent anti-tumor agents Although the novel 5-aza-elliptici

Kinetics and Mechanism of the Bamberger Rearrangement. Part 4. Rearrangement of Sterically Hindered Phenylhydroxylamines to 4-Aminophenols in Aqueous Sulphuric Acid Solution

The rates of the Bamberger rearrangement of sterically hindered phenylhydroxylamines have been determined in aqueous sulphuric acid solution and the substituent effects (in particular, the steric effects) are discussed.The rate constants for phenylhydroxylamines with 2-substituents (Me, Cl, I) satisfied the Taft equation: log krel = ρ*?* - δES with ρ*-1.93 and δ-1.16.The result shows that steric hindrance of the substituents, in addition to the electron-donating effect, has an accelerating effect on the rates of the Bamberger rearrangement.The rate constants for 3-substituted 2-methylphenylhydroxylamines were generally greater than those for 5-substituted 2-methylphenylhydroxylamines.The difference was attributed to the 'buttressing effect' of neighbouring 3-substituents.This is the first example of steric acceleration of the Bamberger rearrangement.